Manipulating intratumoral fenton chemistry for enhanced chemodynamic and chemodynamic‐synergized multimodal therapy

Y Zhou, S Fan, L Feng, X Huang, X Chen - Advanced Materials, 2021‏ - Wiley Online Library
Chemodynamic therapy (CDT) uses the tumor microenvironment‐assisted intratumoral
Fenton reaction for generating highly toxic hydroxyl free radicals (• OH) to achieve selective …

Aggregation‐induced emission: new vistas at the aggregate level

Z Zhao, H Zhang, JWY Lam… - Angewandte Chemie …, 2020‏ - Wiley Online Library
Aggregation‐induced emission (AIE) describes a photophysical phenomenon in which
molecular aggregates exhibit stronger emission than the single molecules. Over the course …

Aggregation‐enhanced theranostics: AIE sparkles in biomedical field

M Kang, Z Zhang, N Song, M Li, P Sun, X Chen… - …, 2020‏ - Wiley Online Library
Theranostics referring to the ingenious integration of diagnostics and therapeutics has
garnered tremendous attention in these years as it provides a promising opportunity for …

Self-indicating polymers: a pathway to intelligent materials

M Bayat, H Mardani, H Roghani-Mamaqani… - Chemical Society …, 2024‏ - pubs.rsc.org
Self-indicating polymers have emerged as a promising class of smart materials that possess
the unique ability to undergo detectable variations in their physical or chemical properties in …

Boron-doped Fe-NC single-atom nanozymes specifically boost peroxidase-like activity

L Jiao, W Xu, Y Zhang, Y Wu, W Gu, X Ge, B Chen… - Nano Today, 2020‏ - Elsevier
Nanomaterials with enzyme-like activities, ie, nanozymes, have aroused wide concern in
biocatalysis. Fe-NC single-atom catalysts with atomically dispersed FeN x as active sites …

Cancer‐cell‐Activated in situ synthesis of mitochondria‐targeting AIE photosensitizer for precise photodynamic therapy

Y Wang, S Xu, L Shi, C Teh, G Qi… - Angewandte Chemie …, 2021‏ - Wiley Online Library
Maximization of phototoxic damage on tumor with minimized side effect on normal tissue is
essential for effective anticancer photodynamic therapy (PDT). This requires highly cancer …

Delivering metal ions by nanomaterials: Turning metal ions into drug-like cancer theranostic agents

C Liu, L Guo, Y Wang, J Zhang, C Fu - Coordination Chemistry Reviews, 2023‏ - Elsevier
Nanomaterials have been extensively used for cancer therapy and diagnosis due to their
designability, multifunctionality, and unique in vivo distribution. Metal ions are increasingly …

Gathering brings strength: How organic aggregates boost disease phototheranostics

J Qi, H Ou, Q Liu, D Ding - Aggregate, 2021‏ - Wiley Online Library
Phototheranostics that concurrently and complementarily integrate real‐time diagnosis and
in situ therapeutic capabilities in one platform has become the advancing edge of precision …

Improving image‐guided surgical and immunological tumor treatment efficacy by photothermal and photodynamic therapies based on a multifunctional NIR AIEgen

R Jiang, J Dai, X Dong, Q Wang, Z Meng… - Advanced …, 2021‏ - Wiley Online Library
Multimodal therapy is attracting increasing attention to improve tumor treatment efficacy, but
generally requires various complicated ingredients combined within one theranostic system …

Activity‐based smart AIEgens for detection, bioimaging, and therapeutics: recent progress and outlook

H Li, H Kim, J Han, VN Nguyen, X Peng, J Yoon - Aggregate, 2021‏ - Wiley Online Library
Activity‐based approaches for designing AIEgens possess prominent advantages including
high selectivity, sensitivity, and signal‐to‐noise ratio, and they have received more attention …