Alzheimer's disease (AD), which is characterized by the presence of amyloid-β (Aβ) plaques
and neurofibrillary tangles, accompanied by neurodegeneration, is the most common form of …

Nobiletin (NOB) chemically known as 5, 6, 7, 8, 3′, 4′‐hexamethoxyflavone is a dietary
polymethoxylated flavonoid found in Citrus fruits. Recent evidences show that NOB is a …

Our society currently faces the twin challenges of resource depletion and waste
accumulation leading to rapidly escalating raw material costs and increasingly expensive …

The studies of nobiletin and other polymethoxyflavones from citrus peels become prevalent
in recent years due to many well-established evidences showing their multiple efficacious …

Aged citrus peels (chenpi) have been used as a dietary supplement for gastrointestinal
health maintenance in China. Recently, it was reported to exhibit anti-obesity activity …

Nobiletin is abundant in citrus peels and demonstrates good anti-obesity bioactivity.
However, its anti-obesity mechanisms still remain unclear. This study aims to explore the …

Alzheimer's disease (AD) is presented as an age-related neurodegenerative disease with
multiple cognitive deficits and amyloid β (Aβ) accumulation is the most important involved …

AMPK is a serine/threonine protein kinase that has the function of maintaining the balance
between ATP production and consumption in most eukaryotic cells. It plays a relevant role in …

Obesity, dyslipidemia, and insulin resistance, the increasingly common metabolic syndrome,
are risk factors for CVD and type 2 diabetes that warrant novel therapeutic interventions. The …

Coenzyme Q10 (CoQ10) is a known anti-adipogenic factor. However, the mechanism by
which CoQ10 acts is unclear. In this study, we found that CoQ10 increased the …