Algorithmic fairness in artificial intelligence for medicine and healthcare
In healthcare, the development and deployment of insufficiently fair systems of artificial
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …
intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models …
Human-in-the-loop machine learning: a state of the art
Researchers are defining new types of interactions between humans and machine learning
algorithms generically called human-in-the-loop machine learning. Depending on who is in …
algorithms generically called human-in-the-loop machine learning. Depending on who is in …
Scaling vision transformers to gigapixel images via hierarchical self-supervised learning
Abstract Vision Transformers (ViTs) and their multi-scale and hierarchical variations have
been successful at capturing image representations but their use has been generally …
been successful at capturing image representations but their use has been generally …
Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance
Tumor-infiltrating T cells offer a promising avenue for cancer treatment, yet their states
remain to be fully characterized. Here we present a single-cell atlas of T cells from 308,048 …
remain to be fully characterized. Here we present a single-cell atlas of T cells from 308,048 …
Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours
Each tumour contains diverse cellular states that underlie intratumour heterogeneity (ITH), a
central challenge of cancer therapeutics. Dozens of recent studies have begun to describe …
central challenge of cancer therapeutics. Dozens of recent studies have begun to describe …
A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors
AB Dohlman, J Klug, M Mesko, IH Gao, SM Lipkin… - Cell, 2022 - cell.com
Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the
human microbiome, yet little is known about their role in human cancers. Pan-cancer …
human microbiome, yet little is known about their role in human cancers. Pan-cancer …
Artificial intelligence: A powerful paradigm for scientific research
Artificial intelligence (AI) coupled with promising machine learning (ML) techniques well
known from computer science is broadly affecting many aspects of various fields including …
known from computer science is broadly affecting many aspects of various fields including …
A novel cuproptosis-related prognostic gene signature and validation of differential expression in clear cell renal cell carcinoma
Z Bian, R Fan, L **e - Genes, 2022 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cell
carcinoma, which is characterized by metabolic reprogramming. Cuproptosis, a novel form …
carcinoma, which is characterized by metabolic reprogramming. Cuproptosis, a novel form …
Multimodal data integration using machine learning improves risk stratification of high-grade serous ovarian cancer
KM Boehm, EA Aherne, L Ellenson, I Nikolovski… - Nature cancer, 2022 - nature.com
Patients with high-grade serous ovarian cancer suffer poor prognosis and variable response
to treatment. Known prognostic factors for this disease include homologous recombination …
to treatment. Known prognostic factors for this disease include homologous recombination …
Structure-based classification predicts drug response in EGFR-mutant NSCLC
Epidermal growth factor receptor (EGFR) mutations typically occur in exons 18–21 and are
established driver mutations in non-small cell lung cancer (NSCLC),–. Targeted therapies …
established driver mutations in non-small cell lung cancer (NSCLC),–. Targeted therapies …