Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

Cerebral palsy—trends in epidemiology and recent development in prenatal mechanisms of disease, treatment, and prevention

M Stavsky, O Mor, SA Mastrolia, S Greenbaum… - Frontiers in …, 2017 - frontiersin.org
Cerebral palsy (CP) is the most common motor disability in childhood. This syndrome is the
manifestation of intrauterine pathologies, intrapartum complications, and the postnatal …

Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics

KR Theis, R Romero, AD Winters, JM Greenberg… - American journal of …, 2019 - Elsevier
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …

Maternal infection and cerebral palsy in infants of normal birth weight

JK Grether, KB Nelson - Jama, 1997 - jamanetwork.com
Context.—Exposure to maternal or placental infection is related to risk of preterm birth and,
in premature infants, of brain lesions predictive of cerebral palsy (CP). Few studies have …

Inflammation in preterm and term labour and delivery

R Romero, J Espinoza, LF Gonçalves… - Seminars in Fetal and …, 2006 - Elsevier
Inflammation has been implicated in the mechanisms responsible for preterm and term
parturition, as well as fetal injury. Out of all of the suspected causes of preterm labour and …

Intrauterine infection and prematurity

LF Gonçalves, T Chaiworapongsa… - Mental retardation and …, 2002 - Wiley Online Library
Intrauterine infection is a major cause of premature labor with and without intact membranes.
Intrauterine infection is present in approximately 25% of all preterm births and the earlier the …

[PDF][PDF] The role of infection in preterm labour and delivery

R Romero, R Gómez, T Chaiworapongsa… - Paediatric and …, 2001 - academia.edu
A strong body of evidence suggests that infection plays a role in the pathogenesis of preterm
labour and delivery. Moreover, recent evidence indicates that intrauterine infection may also …

The frequency and type of placental histologic lesions in term pregnancies with normal outcome

R Romero, YM Kim, P Pacora, CJ Kim… - Journal of perinatal …, 2018 - degruyter.com
Objective To determine the frequency and type of histopathologic lesions in placentas
delivered by women with a normal pregnancy outcome. Methods This retrospective cohort …

[HTML][HTML] A single-cell atlas of the myometrium in human parturition

R Pique-Regi, R Romero, V Garcia-Flores… - JCI insight, 2022 - ncbi.nlm.nih.gov
Parturition is a well-orchestrated process characterized by increased uterine contractility,
cervical ripening, and activation of the chorioamniotic membranes; yet, the transition from a …

[HTML][HTML] Clinical chorioamnionitis at term I: microbiology of the amniotic cavity using cultivation and molecular techniques

R Romero, J Miranda, JP Kusanovic… - Journal of perinatal …, 2015 - degruyter.com
Introduction: The objectives of this study were: 1) to determine the amniotic fluid (AF)
microbiology of patients with the diagnosis of clinical chorioamnionitis at term using both …