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The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
The Drosophila brain contains a relatively simple circuit for forming Pavlovian associations,
yet it achieves many operations common across memory systems. Recent advances have …
yet it achieves many operations common across memory systems. Recent advances have …
Re-evaluating circuit mechanisms underlying pattern separation
NA Cayco-Gajic, RA Silver - Neuron, 2019 - cell.com
When animals interact with complex environments, their neural circuits must separate
overlap** patterns of activity that represent sensory and motor information. Pattern …
overlap** patterns of activity that represent sensory and motor information. Pattern …
The neuronal architecture of the mushroom body provides a logic for associative learning
We identified the neurons comprising the Drosophila mushroom body (MB), an associative
center in invertebrate brains, and provide a comprehensive map describing their potential …
center in invertebrate brains, and provide a comprehensive map describing their potential …
A connectome of a learning and memory center in the adult Drosophila brain
Understanding memory formation, storage and retrieval requires knowledge of the
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
underlying neuronal circuits. In Drosophila, the mushroom body (MB) is the major site of …
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
Animals discriminate stimuli, learn their predictive value and use this knowledge to modify
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …
their behavior. In Drosophila, the mushroom body (MB) plays a key role in these processes …
A neural algorithm for a fundamental computing problem
Similarity search—for example, identifying similar images in a database or similar
documents on the web—is a fundamental computing problem faced by large-scale …
documents on the web—is a fundamental computing problem faced by large-scale …
Cellular diversity in the Drosophila midbrain revealed by single-cell transcriptomics
To understand the brain, molecular details need to be overlaid onto neural wiring diagrams
so that synaptic mode, neuromodulation and critical signaling operations can be considered …
so that synaptic mode, neuromodulation and critical signaling operations can be considered …
[HTML][HTML] Do the right thing: neural network mechanisms of memory formation, expression and update in Drosophila
P Cognigni, J Felsenberg, S Waddell - Current opinion in neurobiology, 2018 - Elsevier
Highlights•Recurrent connectivity is anatomically and functionally prevalent in fly memory
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …
circuits.•Sustained reverberant activity is necessary for memory consolidation.•Feedforward …
Common principles for odour coding across vertebrates and invertebrates
The olfactory system is an ideal and tractable system for exploring how the brain transforms
sensory inputs into behaviour. The basic tasks of any olfactory system include odour …
sensory inputs into behaviour. The basic tasks of any olfactory system include odour …
Heterosynaptic plasticity underlies aversive olfactory learning in Drosophila
Although associative learning has been localized to specific brain areas in many animals,
identifying the underlying synaptic processes in vivo has been difficult. Here, we provide the …
identifying the underlying synaptic processes in vivo has been difficult. Here, we provide the …