Hallmarks of cancer—the new testament

SS Senga, RP Grose - Advances in Surgical and Medical …, 2023 - taylorfrancis.com
Ancient Egyptians believed cancer to be a curse, as seen from evidence as old as 3000 BC
from the Edwin Smith Papyrus which described breast cancer and Ebers Papyrus dated …

Bioresource upgrade for sustainable energy, environment, and biomedicine

F Li, Y Li, KS Novoselov, F Liang, J Meng, SH Ho… - Nano-Micro Letters, 2023 - Springer
We conceptualize bioresource upgrade for sustainable energy, environment, and
biomedicine with a focus on circular economy, sustainability, and carbon neutrality using …

High-throughput and proteome-wide discovery of endogenous biomolecular condensates

P Li, P Chen, F Qi, J Shi, W Zhu, J Li, P Zhang, H **e… - Nature Chemistry, 2024 - nature.com
Phase separation inside mammalian cells regulates the formation of the biomolecular
condensates that are related to gene expression, signalling, development and disease …

Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation

Y Song, H Na, SE Lee, YM Kim, J Moon… - Nature …, 2024 - nature.com
Obesity has emerged as a prominent risk factor for the development of malignant tumors.
However, the existing literature on the role of adipocytes in the tumor microenvironment …

[HTML][HTML] Adipocyte mesenchymal transition contributes to mammary tumor progression

Q Zhu, Y Zhu, C Hepler, Q Zhang, J Park, C Gliniak… - Cell reports, 2022 - cell.com
Obesity is associated with increased cancer incidence and progression. However, the
relationship between adiposity and cancer remains poorly understood at the mechanistic …

Volumetric compression induces intracellular crowding to control intestinal organoid growth via Wnt/β-catenin signaling

Y Li, M Chen, J Hu, R Sheng, Q Lin, X He, M Guo - Cell stem cell, 2021 - cell.com
Enormous amounts of essential intracellular events are crowdedly packed inside picoliter-
sized cellular space. However, the significance of the physical properties of cells remains …

Compressive stresses in cancer: characterization and implications for tumour progression and treatment

JA Linke, LL Munn, RK Jain - Nature Reviews Cancer, 2024 - nature.com
Beyond their many well-established biological aberrations, solid tumours create an
abnormal physical microenvironment that fuels cancer progression and confers treatment …

Cancer-associated adipocytes in breast cancer: Causes and consequences

I Rybinska, N Mangano, E Tagliabue… - International journal of …, 2021 - mdpi.com
Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …

V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding …

J Ou, Z Zhou, R Dai, J Zhang, S Zhao, X Wu… - Journal of …, 2021 - journals.asm.org
The current pandemic of COVID-19 is caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …

Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin

T van der Wal, R Van Amerongen - Open Biology, 2020 - royalsocietypublishing.org
CTNNB1 (catenin β-1, also known as β-catenin) plays a dual role in the cell. It is the key
effector of WNT/CTNNB1 signalling, acting as a transcriptional co-activator of TCF/LEF target …