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Hallmarks of cancer—the new testament
SS Senga, RP Grose - Advances in Surgical and Medical …, 2023 - taylorfrancis.com
Ancient Egyptians believed cancer to be a curse, as seen from evidence as old as 3000 BC
from the Edwin Smith Papyrus which described breast cancer and Ebers Papyrus dated …
from the Edwin Smith Papyrus which described breast cancer and Ebers Papyrus dated …
Bioresource upgrade for sustainable energy, environment, and biomedicine
We conceptualize bioresource upgrade for sustainable energy, environment, and
biomedicine with a focus on circular economy, sustainability, and carbon neutrality using …
biomedicine with a focus on circular economy, sustainability, and carbon neutrality using …
High-throughput and proteome-wide discovery of endogenous biomolecular condensates
Phase separation inside mammalian cells regulates the formation of the biomolecular
condensates that are related to gene expression, signalling, development and disease …
condensates that are related to gene expression, signalling, development and disease …
Dysfunctional adipocytes promote tumor progression through YAP/TAZ-dependent cancer-associated adipocyte transformation
Y Song, H Na, SE Lee, YM Kim, J Moon… - Nature …, 2024 - nature.com
Obesity has emerged as a prominent risk factor for the development of malignant tumors.
However, the existing literature on the role of adipocytes in the tumor microenvironment …
However, the existing literature on the role of adipocytes in the tumor microenvironment …
[HTML][HTML] Adipocyte mesenchymal transition contributes to mammary tumor progression
Obesity is associated with increased cancer incidence and progression. However, the
relationship between adiposity and cancer remains poorly understood at the mechanistic …
relationship between adiposity and cancer remains poorly understood at the mechanistic …
Volumetric compression induces intracellular crowding to control intestinal organoid growth via Wnt/β-catenin signaling
Enormous amounts of essential intracellular events are crowdedly packed inside picoliter-
sized cellular space. However, the significance of the physical properties of cells remains …
sized cellular space. However, the significance of the physical properties of cells remains …
Compressive stresses in cancer: characterization and implications for tumour progression and treatment
JA Linke, LL Munn, RK Jain - Nature Reviews Cancer, 2024 - nature.com
Beyond their many well-established biological aberrations, solid tumours create an
abnormal physical microenvironment that fuels cancer progression and confers treatment …
abnormal physical microenvironment that fuels cancer progression and confers treatment …
Cancer-associated adipocytes in breast cancer: Causes and consequences
I Rybinska, N Mangano, E Tagliabue… - International journal of …, 2021 - mdpi.com
Breast cancer progression is highly dependent on the heterotypic interaction between tumor
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …
cells and stromal cells of the tumor microenvironment. Cancer-associated adipocytes …
V367F mutation in SARS-CoV-2 spike RBD emerging during the early transmission phase enhances viral infectivity through increased human ACE2 receptor binding …
J Ou, Z Zhou, R Dai, J Zhang, S Zhao, X Wu… - Journal of …, 2021 - journals.asm.org
The current pandemic of COVID-19 is caused by a novel coronavirus, severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
respiratory syndrome coronavirus 2 (SARS-CoV-2). The SARS-CoV-2 spike protein receptor …
Walking the tight wire between cell adhesion and WNT signalling: a balancing act for β-catenin
T van der Wal, R Van Amerongen - Open Biology, 2020 - royalsocietypublishing.org
CTNNB1 (catenin β-1, also known as β-catenin) plays a dual role in the cell. It is the key
effector of WNT/CTNNB1 signalling, acting as a transcriptional co-activator of TCF/LEF target …
effector of WNT/CTNNB1 signalling, acting as a transcriptional co-activator of TCF/LEF target …