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The potential of triplet combination therapies for patients with FLT3-ITD-mutated acute myeloid leukemia
A Bruzzese, E Vigna, EA Martino… - Expert Review of …, 2024 - Taylor & Francis
Introduction Acute myeloid leukemia (AML) encompasses a heterogeneous group of
aggressive myeloid malignancies, where FMS-like tyrosine kinase 3 (FLT3) mutations are …
aggressive myeloid malignancies, where FMS-like tyrosine kinase 3 (FLT3) mutations are …
Genetic, phenotypic, and clinical heterogeneity of NPM1-mutant acute myeloid leukemias
The current classification of acute myeloid leukemia (AML) relies largely on genomic
alterations. AML with mutated nucleophosmin 1 (NPM1-mut) is the largest of the genetically …
alterations. AML with mutated nucleophosmin 1 (NPM1-mut) is the largest of the genetically …
Evolution from an antecedent chronic myeloid malignancy does not impact survival outcomes in NPM1‐mutated AML
Abstract Nucleophosmin‐1 (NPM1)‐mutated AML is a molecularly defined subtype typically
associated with favorable treatment response and prognosis; however, its prognostic …
associated with favorable treatment response and prognosis; however, its prognostic …