There is a saying,“Eyes are the windows to the soul”. In much the same vein, blood, since it
flows through the entire body, can be considered the window to the physical condition of the …

Mass spectrometry (MS)-based top-down proteomics characterizes complex proteomes at
the intact proteoform level and provides an accurate picture of protein isoforms and protein …

Revised and updated, Chemical Reagents for Protein Modification, Third Edition is an
encyclopedic work describing the many approaches to the site-specific modification of …

Laypersons, researchers and clinicians alike speak of the biotechnology revolution with
excitement. Media coverage of new breakthroughs in medicine often have the public and the …

Current solution based proteomic analysis methods are generally based on enzymatic
digestion of a protein mixture followed by separation using multidimensional liquid …

Mechanistic studies of cellular processes are usually carried out with large populations of
cells. However, parameters that are measured as averages of large populations can be …

Methods are described to achieve more efficient multidimensional protein separation in a
microfluidic channel. The new methods couple isoelectric focusing (IEF) with high ionic …

High-efficiency, two-dimensional separations of tryptic digests were achieved using glass
microfluidic devices. Following micellar electrokinetic chromatography (MEKC) separations …

Mass spectrometry (MS)‐based proteomics is currently dominated by the analysis of
peptides originating either from digestion of proteins separated by two‐dimensional gel …

Synthetic biology is a rapidly growing multidisciplinary branch of science which aims to
mimic complex biological systems by creating similar forms. Constructing an artificial system …