A systematic review of direct outputs from the cerebellum to the brainstem and diencephalon in mammals

M Novello, LWJ Bosman, CI De Zeeuw - The Cerebellum, 2024 - Springer
The cerebellum is involved in many motor, autonomic and cognitive functions, and new
tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously …

Identification of shared and differentiating genetic architecture for autism spectrum disorder, attention-deficit hyperactivity disorder and case subgroups

M Mattheisen, J Grove, TD Als, J Martin, G Voloudakis… - Nature Genetics, 2022 - nature.com
Attention-deficit hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) are
highly heritable neurodevelopmental conditions, with considerable overlap in their genetic …

Recent advances in the understanding of specific efferent pathways emerging from the cerebellum

S Kang, S Jun, SJ Baek, H Park, Y Yamamoto… - Frontiers in …, 2021 - frontiersin.org
The cerebellum has a long history in terms of research on its network structures and motor
functions, yet our understanding of them has further advanced in recent years owing to …

Genome-wide analyses of individual differences in quantitatively assessed reading-and language-related skills in up to 34,000 people

E Eising, N Mirza-Schreiber… - Proceedings of the …, 2022 - National Acad Sciences
The use of spoken and written language is a fundamental human capacity. Individual
differences in reading-and language-related skills are influenced by genetic variation, with …

CSF-derived extracellular vesicles from patients with Parkinson's disease induce symptoms and pathology

S Herman, R Djaldetti, B Mollenhauer, D Offen - Brain, 2023 - academic.oup.com
Parkinson's disease is characterized by the gradual appearance of intraneuronal inclusions
that are primarily composed of misfolded α-synuclein protein, leading to cytotoxicity and …

VTA-projecting cerebellar neurons mediate stress-dependent depression-like behaviors

SJ Baek, JS Park, J Kim, Y Yamamoto… - Elife, 2022 - elifesciences.org
Although cerebellar alterations have been implicated in stress symptoms, the exact
contribution of the cerebellum to stress symptoms remains to be elucidated. Here, we …

Brainstem neuromelanin and iron MRI reveals a precise signature for idiopathic and LRRK2 Parkinson's disease

M Martínez, M Ariz, I Alvarez, G Castellanos… - npj Parkinson's …, 2023 - nature.com
Neuromelanin (NM) loss in substantia nigra pars compacta (SNc) and locus coeruleus (LC)
reflects neuronal death in Parkinson's disease (PD). Since genetically-determined PD …

Cerebellar prediction and feeding behaviour

CI Iosif, ZI Bashir, R Apps, J Pickford - The Cerebellum, 2023 - Springer
Given the importance of the cerebellum in controlling movements, it might be expected that
its main role in eating would be the control of motor elements such as chewing and …

Upper and Lower Limb Motor Function Correlates with Ipsilesional Corticospinal Tract and Red Nucleus Structural Integrity in Chronic Stroke: A Cross‐Sectional, ROI …

DM Peters, J Fridriksson, JD Richardson… - Behavioural …, 2021 - Wiley Online Library
Background. Structural integrity of the ipsilesional corticospinal tract (CST) is important for
upper limb motor recovery after stroke. However, additional neuromechanisms associated …

Networking of the human cerebellum: From anatomo-functional development to neurosurgical implications

A De Benedictis, MC Rossi-Espagnet… - Frontiers in …, 2022 - frontiersin.org
In the past, the cerebellum was considered to be substantially involved in sensory-motor
coordination. However, a growing number of neuroanatomical, neuroimaging, clinical and …