Treatment of posttraumatic stress disorder: a state-of-the-art review

L Burback, S Brult-Phillips, MJ Nijdam… - Current …, 2024 - benthamdirect.com
This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Neurobiology of early life adversity: A systematic review of meta-analyses towards an integrative account of its neurobiological trajectories to mental disorders

Y Hakamata, Y Suzuki, H Kobashikawa… - Frontiers in …, 2022 - Elsevier
Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of develo** mental disorders in later life. However, no review has …

Memories are not written in stone: Re-writing fear memories by means of non-invasive brain stimulation and optogenetic manipulations

S Borgomaneri, S Battaglia, G Sciamanna… - Neuroscience & …, 2021 - Elsevier
The acquisition of fear associative memory requires brain processes of coordinated neural
activity within the amygdala, prefrontal cortex (PFC), hippocampus, thalamus and brainstem …

The role of Serotonin in fear learning and memory: A systematic review of human studies

F Tortora, AL Hadipour, S Battaglia, A Falzone… - Brain Sciences, 2023 - mdpi.com
Fear is characterized by distinct behavioral and physiological responses that are essential
for the survival of the human species. Fear conditioning (FC) serves as a valuable model for …

Prefrontal-hippocampal interactions supporting the extinction of emotional memories: the retrieval stop** model

MC Anderson, SB Floresco - Neuropsychopharmacology, 2022 - nature.com
Neuroimaging has revealed robust interactions between the prefrontal cortex and the
hippocampus when people stop memory retrieval. Efforts to stop retrieval can arise when …

[HTML][HTML] Alleviating anxiety and taming trauma: novel pharmacotherapeutics for anxiety disorders and posttraumatic stress disorder

N Singewald, SB Sartori, A Reif, A Holmes - Neuropharmacology, 2023 - Elsevier
Psychiatric disorders associated with psychological trauma, stress and anxiety are a highly
prevalent and increasing cause of morbidity worldwide. Current therapeutic approaches …

From childhood adversity to latent stress vulnerability in adulthood: the mediating roles of sleep disturbances and HPA axis dysfunction

L Simon, R Admon - Neuropsychopharmacology, 2023 - nature.com
Childhood adversity is a prominent predisposing risk factor for latent stress vulnerability,
expressed as an elevated likelihood of develo** stress-related psychopathology upon …

Abnormal dynamic functional connectivity during fear extinction learning in PTSD and anxiety disorders

Z Wen, J Seo, EF Pace-Schott, MR Milad - Molecular psychiatry, 2022 - nature.com
Examining the neural circuits of fear/threat extinction advanced our mechanistic
understanding of several psychiatric disorders, including anxiety disorders (AX) and …

Human fear conditioning: From neuroscience to the clinic

MA Fullana, JE Dunsmoor, KRJ Schruers… - Behaviour research and …, 2020 - Elsevier
Both clinicians and neuroscientists have been long interested in the topic of fear
conditioning, with recent advances in neuroscience, in particular, igniting a shared interest …

[HTML][HTML] Functional neuroimaging in PTSD: from discovery of underlying mechanisms to addressing diagnostic heterogeneity

Y Neria - American Journal of Psychiatry, 2021 - Am Psychiatric Assoc
Exposure to trauma is highly common worldwide (1), ranging from interpersonal assaults to
disasters, wars, and pandemics. Ensuing trauma-related psychopathology is common …