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The human epidermal basement membrane: a shaped and cell instructive platform that aging slowly alters
One of the most important functions of skin is to act as a protective barrier. To fulfill this role,
the structural integrity of the skin depends on the dermal-epidermal junction—a complex …
the structural integrity of the skin depends on the dermal-epidermal junction—a complex …
Collagen biosynthesis, processing, and maturation in lung ageing
In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical
regulator of cell function by virtue of specific physical, biochemical, and mechanical …
regulator of cell function by virtue of specific physical, biochemical, and mechanical …
[HTML][HTML] Alterations in extracellular matrix composition during aging and photoaging of the skin
Human skin is composed of the cell-rich epidermis, the extracellular matrix (ECM) rich
dermis, and the hypodermis. Within the dermis, a dense network of ECM proteins provides …
dermis, and the hypodermis. Within the dermis, a dense network of ECM proteins provides …
To form and function: on the role of basement membrane mechanics in tissue development, homeostasis and disease
The basement membrane (BM) is a special type of extracellular matrix that lines the basal
side of epithelial and endothelial tissues. Functionally, the BM is important for providing …
side of epithelial and endothelial tissues. Functionally, the BM is important for providing …
Aging alters functionally human dermal papillary fibroblasts but not reticular fibroblasts: a new view of skin morphogenesis and aging
S Mine, NO Fortunel, H Pageon, D Asselineau - PloS one, 2008 - journals.plos.org
Understanding the contribution of the dermis in skin aging is a key question, since this tissue
is particularly important for skin integrity, and because its properties can affect the epidermis …
is particularly important for skin integrity, and because its properties can affect the epidermis …
New concepts in basement membrane biology
Basement membranes (BMs) are thin sheets of extracellular matrix that outline epithelia,
muscle fibers, blood vessels and peripheral nerves. The current view of BM structure and …
muscle fibers, blood vessels and peripheral nerves. The current view of BM structure and …
Estrogen and skin: an overview
MG Shah, HI Maibach - American journal of clinical dermatology, 2001 - Springer
As the population of postmenopausal women increases, interest in the effects of estrogen
grows. The influence of estrogen on several body systems has been well-documented; …
grows. The influence of estrogen on several body systems has been well-documented; …
[HTML][HTML] The impact of intrinsic ageing on the protein composition of the dermal-epidermal junction
The dermal-epidermal junction of human skin exhibits age-related remodelling, resulting in
a flattened appearance and reduced surface area. Despite this, a paucity of information is …
a flattened appearance and reduced surface area. Despite this, a paucity of information is …
Characterization of type I and IV collagens by Raman microspectroscopy: identification of spectral markers of the dermo‐epidermal junction
Type I and IV collagens are important constituents of the skin. Type I collagen is found in all
dermal layers in high proportion, while type IV collagen is localized in the basement …
dermal layers in high proportion, while type IV collagen is localized in the basement …
Managing urogenital atrophy
S Palacios - Maturitas, 2009 - Elsevier
The objective of this review is to provide a practical guide on the diagnosis and clinical
management of urogenital atrophy. A literature search was done in Medline (1969–2008) for …
management of urogenital atrophy. A literature search was done in Medline (1969–2008) for …