Physicochemical hydrodynamics of droplets out of equilibrium

D Lohse, X Zhang - Nature Reviews Physics, 2020‏ - nature.com
Droplets abound in nature and technology. In general, they are multicomponent, and, when
out of equilibrium, have gradients in concentration, implying flow and mass transport …

Principles of nanoparticle formation by flash nanoprecipitation

WS Saad, RK Prud'homme - Nano Today, 2016‏ - Elsevier
Rapid precipitation is an efficient approach for engineering materials at the nanoscale. By
controlling solute nucleation and growth rates in solvent precipitation processes, the size of …

Control of polymeric nanoparticle size to improve therapeutic delivery

JW Hickey, JL Santos, JM Williford, HQ Mao - Journal of Controlled …, 2015‏ - Elsevier
As nanoparticle (NP)-mediated drug delivery research continues to expand, understanding
parameters that govern NP interactions with the biological environment becomes …

Review of long-wavelength optical and NIR imaging materials: contrast agents, fluorophores, and multifunctional nano carriers

VJ Pansare, S Hejazi, WJ Faenza… - Chemistry of …, 2012‏ - ACS Publications
The importance of long wavelength and near-infrared (NIR) imaging has dramatically
increased due to the desire to perform whole animal and deep tissue imaging. The adoption …

Controlling drug nanoparticle formation by rapid precipitation

SM D'Addio, RK Prud'homme - Advanced drug delivery reviews, 2011‏ - Elsevier
Nanoparticles are a drug delivery platform that can enhance the efficacy of active
pharmaceutical ingredients, including poorly-water soluble compounds, ionic drugs …

Polymeric nanoparticles and microparticles for the delivery of peptides, biologics, and soluble therapeutics

RF Pagels, RK Prud'Homme - Journal of Controlled Release, 2015‏ - Elsevier
Biologically derived therapeutics, or biologics, are the most rapidly growing segment of the
pharmaceutical marketplace. However, there are still unmet needs in improving the delivery …

Multifunctional nanoparticles for imaging, delivery and targeting in cancer therapy

ME Gindy, RK Prud'homme - Expert opinion on drug delivery, 2009‏ - Taylor & Francis
The application of nanoparticles for the delivery and targeting of pharmaceutical, therapeutic
and diagnostic agents in cancer therapy has received significant attention in recent years …

A versatile and robust platform for the scalable manufacture of biomimetic nanovaccines

H Hu, C Yang, F Zhang, M Li, Z Tu, L Mu… - Advanced …, 2021‏ - Wiley Online Library
Biomimetic strategies are useful for designing potent vaccines. Decorating a nanoparticulate
adjuvant with cell membrane fragments as the antigen‐presenting source exemplifies, such …

A simple confined im**ement jets mixer for flash nanoprecipitation

J Han, Z Zhu, H Qian, AR Wohl, CJ Beaman… - Journal of …, 2012‏ - Elsevier
ABSTRACT Johnson and Prud′ homme (2003. AICHE J 49: 2264–2282) introduced the
confined im**ement jets (CIJ) mixer to prepare nanoparticles loaded with hydrophobic …

Flash nanoprecipitation: particle structure and stability

KM Pustulka, AR Wohl, HS Lee, AR Michel… - Molecular …, 2013‏ - ACS Publications
Flash nanoprecipitation (FNP) is a process that, through rapid mixing, stabilizes an insoluble
low molecular weight compound in a nanosized, polymer-stabilized delivery vehicle. The …