Periodontitis and cardiovascular diseases: Consensus report

M Sanz, A Marco del Castillo, S Jepsen… - Journal of clinical …, 2020 - Wiley Online Library
Abstract Background In Europe cardiovascular disease (CVD) is responsible for 3.9 million
deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to …

[HTML][HTML] Periodontitis: a multifaceted disease of tooth-supporting tissues

E Könönen, M Gursoy, UK Gursoy - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is an infection-driven inflammatory disease in which the composition of biofilms
plays a significant role. Dental plaque accumulation at the gingival margin initiates an …

Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier

LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan… - Science, 2021 - science.org
INTRODUCTION Mucosal barrier sites are continuously exposed to diverse environmental
stimuli, and the fine-tuning of mucosal tissue–specific immune responses is key to …

[LIVRE][B] Newman and Carranza's Clinical Periodontology E-Book: Newman and Carranza's Clinical Periodontology E-Book

MG Newman, H Takei, PR Klokkevold, FA Carranza - 2018 - books.google.com
From basic science and fundamental procedures to the latest advanced techniques in
reconstructive, esthetic, and implant therapy, Newman and Carranza's Clinical …

A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans

N Dutzan, T Kajikawa, L Abusleme… - Science translational …, 2018 - science.org
Periodontitis is one of the most common human inflammatory diseases, yet the mechanisms
that drive immunopathology and could be therapeutically targeted are not well defined …

Oxidative stress and antioxidant system in periodontitis

Y Wang, O Andrukhov, X Rausch-Fan - Frontiers in physiology, 2017 - frontiersin.org
Periodontitis is a common inflammatory disease, which is initiated by bacterial infection and
subsequently progressed by aberrant host response. It can result in the destruction of teeth …

The role of the host—Neutrophil biology

ILC Chapple, J Hirschfeld, A Kantarci… - Periodontology …, 2023 - Wiley Online Library
Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with
lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial …

[HTML][HTML] Functional biomaterials for comprehensive periodontitis therapy

J Luan, R Li, W Xu, H Sun, Q Li, D Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Periodontitis is an inflammatory disease caused by bacterial infection directly, and the
dysregulation of host immune-inflammatory response finally destroys periodontal tissues …

Periodontal diseases and association with atherosclerotic disease

D Herrera, A Molina, K Buhlin, B Klinge - Periodontology 2000, 2020 - Wiley Online Library
Cardiovascular diseases still account for the majority of deaths worldwide, although
significant improvements in survival, after being affected by cardiovascular disease, have …

Revisiting the Page & Schroeder model: the good, the bad and the unknowns in the periodontal host response 40 years later

G Hajishengallis, JM Korostoff - Periodontology 2000, 2017 - Wiley Online Library
In their classic 1976 paper, Page & Schroeder described the histopathologic events and the
types of myeloid cells and lymphocytes involved in the initiation and progression of …