Preventing Parkinson's disease: an environmental agenda

BR De Miranda, SM Goldman… - Journal of …, 2022 - journals.sagepub.com
Fueled by aging populations and continued environmental contamination, the global burden
of Parkinson's disease (PD) is increasing. The disease, or more appropriately diseases …

Sex differences in movement disorders

S Meoni, A Macerollo, E Moro - Nature Reviews Neurology, 2020 - nature.com
In a range of neurological conditions, including movement disorders, sex-related differences
are emerging not only in brain anatomy and function, but also in pathogenesis, clinical …

The role of sex and sex hormones in neurodegenerative diseases

E Vegeto, A Villa, S Della Torre, V Crippa… - Endocrine …, 2020 - academic.oup.com
Neurodegenerative diseases (NDs) are a wide class of disorders of the central nervous
system (CNS) with unknown etiology. Several factors were hypothesized to be involved in …

The effect of estrogen replacement therapy on Alzheimer's disease and Parkinson's disease in postmenopausal women: a meta-analysis

Y Song, S Li, X Li, X Chen, Z Wei, Q Liu… - Frontiers in …, 2020 - frontiersin.org
Background: Estrogen replacement therapy (ERT) is a common treatment method for
menopausal syndrome; however, its therapeutic value for the treatment of neurological …

You've got male: Sex and the microbiota-gut-brain axis across the lifespan

M Jaggar, K Rea, S Spichak, TG Dinan… - Frontiers in …, 2020 - Elsevier
Sex is a critical factor in the diagnosis and development of a number of mental health
disorders including autism, schizophrenia, depression, anxiety, Parkinson's disease …

Sex specific cognitive differences in Parkinson disease

TH Reekes, CI Higginson, CR Ledbetter… - npj Parkinson's …, 2020 - nature.com
Parkinson disease (PD) is a progressive neurodegenerative disorder that is 1.5 times more
common in males than in females. While motor progression tends to be more aggressive in …

Gender gap in deep brain stimulation for Parkinson's disease

ST Jost, L Strobel, A Rizos, PA Loehrer… - npj Parkinson's …, 2022 - nature.com
Previous studies have shown less access to deep brain stimulation (DBS) for Parkinson's
disease (PD) in women compared to men raising concerns about a potential gender gap …

Cellular and molecular pathophysiology in the progression of Parkinson's disease

V Zaman, DC Shields, R Shams, KP Drasites… - Metabolic brain …, 2021 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder etiologically linked to the loss of
substantia nigra (SN) dopaminergic neurons in the mid-brain. The etiopathology of sporadic …

Sex effects on brain structure in de novo Parkinson's disease: a multimodal neuroimaging study

C Tremblay, N Abbasi, Y Zeighami, Y Yau, M Dadar… - Brain, 2020 - academic.oup.com
Parkinson's disease varies in severity and age of onset. One source of this variability is sex.
Males are twice as likely as females to develop Parkinson's disease, and tend to have more …

Sex and gender differences in Alzheimer's disease, Parkinson's disease, and Amyotrophic Lateral Sclerosis: A narrative review

A Nicoletti, R Baschi, CE Cicero, S Iacono… - Mechanisms of ageing …, 2023 - Elsevier
Abstract Neurodegenerative diseases (NDs), including Alzheimer's disease (AD),
Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), exhibit high phenotypic …