Reverse screening methods to search for the protein targets of chemopreventive compounds

H Huang, G Zhang, Y Zhou, C Lin, S Chen, Y Lin… - Frontiers in …, 2018 - frontiersin.org
This article is a systematic review of reverse screening methods used to search for the
protein targets of chemopreventive compounds or drugs. Typical chemopreventive …

[PDF][PDF] Recent insights into β-Carboline alkaloids with anticancer potential

KL Manasa, SS Yadav, D Srikanth, N Nagesh… - IOSR J. Pharm. Biol …, 2020 - academia.edu
Kesari Lakshmi Manasa,* a Sanam Swetha Yadav, a Danaboina Srikanth, a Narayana
Nagesh,* b and Mallika Alvala* a aDepartment of Medicinal Chemistry, National Institute of …

A new methodology to create polymeric nanocarriers containing hydrophilic low molecular-weight drugs: a green strategy providing a very high drug loading

MG Villamizar-Sarmiento, EF Molina-Soto… - Molecular …, 2019 - ACS Publications
To date, a large number of active molecules are hydrophilic and aromatic low molecular-
weight drugs (HALMD). Unfortunately, the low capacity of these molecules to interact with …

Copalic acid: occurrence, chemistry, and biological activities

VG Medeiros, FJ Durán, KL Lang - Revista Brasileira de Farmacognosia, 2021 - Springer
Copalic acid is a naturally occurring labdane‐type diterpene acid usually isolated from
oleoresins of Copaifera trees, being considered the biomarker for the genus. This compound …

New triterpene sulfates from Vietnamese red alga Tricleocarpa fragilis and their α-glucosidase inhibitory activity

TVA Tran, VM Nguyen, TAN Nguyen… - Journal of Asian …, 2021 - Taylor & Francis
Three new compounds (methyl-3 β, 25-dihydroxycycloart-23-en-29-oate 3-sulfate (1), methyl-
3 β-hydroxy-25-methoxycycloart-23-en-29-oate 3-sulfate (2) and 3 β-hydroxy-25 …

[PDF][PDF] The β-carboline alkaloids in cancer therapy-recent advancements in this area

KL Manasa, SS Yadav, N Nagesh - Journal of Pharmacy and …, 2020 - researchgate.net
Corresponding author: Narayana Nagesh. Abstract: Nature inspired new drug molecules are
developed through the medicinal chemistry approach has a great success in drug discovery …

Discovery of a natural PI3Kδ inhibitor through virtual screening and biological assay study

JF Guo, ZQ Ning, X Wu, YJ Qiao, X Wang - Biochemical and biophysical …, 2019 - Elsevier
Abstract Phosphoinositide-3-kinase-δ (PI3Kδ) is a key regulator in the process of IgE
mediated mast cell degranulation, which directly induces allergic diseases, such as asthma …

Investigation into the Quantitative Structure‐Biotoxicity Relationship of Antibiotics and their Estrogenic Receptor Disruption Effects

W Zhu, S Chen, Y Wang, X Xu, X Huang… - Chemistry & … - Wiley Online Library
In light of antibiotics being classified as environmental hormone‐like compounds, their
interference with the endocrine system has significantly impacted human health and …

[引用][C] Synthesis and Spectra Study, Molecular Modeling, for Biological Activity of Some Drug–Based Metal Complexes

HTA Alzubaidi - 2023 - KING ABDULAZIZ UNIVERSITY

[引用][C] Synthesis, Characterization and Biological Studies of Schiff Bases Metal Complexes

HBM Howsaui, R al-Thani