Mass spectrometry is the driving force behind current brain proteome analysis. In a typical
proteomics approach, a protein isolate is digested into tryptic peptides and then analyzed by …

The development of aquaculture is closely related to human life. Crustaceans play essential
roles in aquaculture. However, the cultivation of crustaceans has been plagued by various …

The subcommissural organ (SCO) is a gland located at the entrance of the aqueduct of
Sylvius in the brain. It exists in species as distantly related as amphioxus and humans, but its …

Biological processes unfold across broad spatial and temporal dimensions, and
measurement of the underlying molecular world is essential to their understanding …

Endogenous peptide hormones represent an essential class of biomolecules, which
regulate cell–cell communications in diverse physiological processes of organisms. Mass …

Due to their involvement in numerous biochemical pathways, neuropeptides have been the
focus of many recent research studies. Unfortunately, classic analytical methods, such as …

The crab Cancer borealis nervous system is an important model for understanding neural
circuit dynamics and modulation, but the identity of neuromodulatory substances and their …

Method optimization is crucial for successful mass spectrometry (MS) analysis. However,
extensive method assessments, altering various parameters individually, are rarely …

Background Proteomics is an analytical technique employed for the identification and
quantitative analysis of total protein content in a cell, tissue or organism using various …

Neuropeptides (NPs), a unique class of neuronal signaling molecules, participate in a
variety of physiological processes and diseases. Quantitative measurements of NPs provide …