[HTML][HTML] AGEs and RAGE: Metabolic and molecular signatures of the glycation-inflammation axis in malignant or metastatic cancers

G Palanissami, SFD Paul - Exploration of Targeted Anti-tumor …, 2023 - ncbi.nlm.nih.gov
From attributing mutations to cancers with the advent of cutting-edge genetic technology in
recent decades, to re-searching the age-old theory of intrinsic metabolic shift of cancers …

[HTML][HTML] GJA1-20k, a Short Isoform of Connexin43, from Its Discovery to Its Potential Implication in Cancer Progression

S Fournier, J Clarhaut, L Cronier, A Monvoisin - Cells, 2025 - mdpi.com
The Connexin43 transmembrane protein (Cx43), encoded by the GJA1 gene, is a member
of a multigenic family of proteins that oligomerize to form hemichannels and intercellular …

Exploring the prognostic significance of lactate-mitochondria-related genes in prostate cancer

Y Wang, R Chen, FL Jiang, X Jiang, Y Zhou… - Frontiers in …, 2025 - frontiersin.org
Prostate cancer (PCa) is a common and serious health issue among older men globally.
Metabolic reprogramming, particularly involving lactate and mitochondria, plays a key role in …

Comprehensive overview of how to fade into succinate dehydrogenase dysregulation in cancer cells by naringenin-loaded chitosan nanoparticles

EM Ragab, AA Khamis, DME Gamal, TM Mohamed - Genes & Nutrition, 2024 - Springer
Mitochondrial respiration complexes play a crucial function. As a result, dysfunction or
change is intimately associated with many different diseases, among them cancer. The …

Identification of the mitochondrial protein POLRMT as a potential therapeutic target of prostate cancer

X Li, L Yao, T Wang, X Gu, Y Wu, T Jiang - Cell Death & Disease, 2023 - nature.com
RNA polymerase mitochondria (POLRMT) is essential for mitochondrial transcription
machinery and other mitochondrial functions. Its expression and potential functions in …

Non-coding RNA and reprogrammed mitochondrial metabolism in genitourinary cancer

S Thirunavukkarasu, S Banerjee, I Tantray… - Frontiers in …, 2024 - frontiersin.org
Non-coding ribonucleic acids (ncRNAs) have been recently shown to contribute to
tumorigenesis by mediating changes in metabolism. ncRNAs act as key molecules in …

Targeting mitochondria and programmed cell death as potential interventions for metastatic castration-resistant prostate cancer

A Amantakul, A Amantakul… - Clinical and …, 2024 - Springer
Prostate cancer is one of the major causes of morbidity and mortality in men worldwide. Most
patients with prostate cancer will turn into end-of-life stage when those tumor cells become …

Mitochondrial metabolism

H Shyam, M Jain, AK Pandey, A Kumar - Metabolomics of Bladder Cancer, 2025 - Elsevier
Bladder cancer stands as a prevalent and lethal malignancy within the realm of urinary tract
diseases, its global prevalence and mortality rates casting a long shadow over public health …

Voluntary Exercise Attenuates Tumor Growth in a Preclinical Model of Castration-Resistant Prostate Cancer

N Berger, B Kugler, D Han, M Li, P Nguyen… - bioRxiv, 2024 - biorxiv.org
Purpose: To examine the effects of voluntary exercise training on tumor growth and explore
the underlying intratumoral molecular pathways and processes responsible for the …

The Regulation Impact of Naringenin-loaded Chitosan Nanoparticles on Succinate Dehydrogenase Activity in Cancer Cells

EM Ragab, AA Khamis, DM El Gamal… - Journal of Cellular …, 2023 - scientificarchives.com
Oxidative phosphorylation dysregulation (OXPHOS) has been demonstrated to be essential
for the development of cancer. Therefore, it may be argued that chaperone and deacetylase …