Coronavirus envelope protein: current knowledge

D Schoeman, BC Fielding - Virology journal, 2019 - Springer
Abstract Background Coronaviruses (CoVs) primarily cause enzootic infections in birds and
mammals but, in the last few decades, have shown to be capable of infecting humans as …

Human coronavirus: host-pathogen interaction

TS Fung, DX Liu - Annual review of microbiology, 2019 - annualreviews.org
Human coronavirus (HCoV) infection causes respiratory diseases with mild to severe
outcomes. In the last 15 years, we have witnessed the emergence of two zoonotic, highly …

[HTML][HTML] SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development

S Zhou, P Lv, M Li, Z Chen, H **n, S Reilly… - Biomedicine & …, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a devastating
global pandemic, which has seriously affected human health worldwide. The discovery of …

The SARS-coronavirus infection cycle: a survey of viral membrane proteins, their functional interactions and pathogenesis

NA Wong, MH Saier Jr - International journal of molecular sciences, 2021 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …

Post-translational modifications of coronavirus proteins: roles and function

TS Fung, DX Liu - Future virology, 2018 - Taylor & Francis
Post-translational modifications (PTMs) refer to the covalent modifications of polypeptides
after they are synthesized, adding temporal and spatial regulation to modulate protein …

SARS-CoV-2 E protein is a potential ion channel that can be inhibited by Gliclazide and Memantine

PPS Tomar, IT Arkin - Biochemical and Biophysical Research …, 2020 - Elsevier
COVID-19 is one of the most impactful pandemics in recorded history. As such, the
identification of inhibitory drugs against its etiological agent, SARS-CoV-2, is of utmost …

Coronavirus proteins as ion channels: current and potential research

C McClenaghan, A Hanson, SJ Lee… - Frontiers in …, 2020 - frontiersin.org
Coronavirus (CoV) outbreaks have recently emerged as a global public health threat due to
their exceptional zoonotic potential—a feature arising from their ability to infect a diverse …

The infectious bronchitis coronavirus envelope protein alters Golgi pH to protect the spike protein and promote the release of infectious virus

JW Westerbeck, CE Machamer - Journal of virology, 2019 - journals.asm.org
Coronaviruses (CoVs) assemble by budding into the lumen of the early Golgi complex prior
to exocytosis. The small CoV envelope (E) protein plays roles in assembly, virion release …

Host-membrane interacting interface of the SARS coronavirus envelope protein: Immense functional potential of C-terminal domain

S Mukherjee, D Bhattacharyya, A Bhunia - Biophysical chemistry, 2020 - Elsevier
The Envelope (E) protein in SARS Coronavirus (CoV) is a small structural protein,
incorporated as part of the envelope. A major fraction of the protein has been known to be …

Regulation of the ER stress response by the ion channel activity of the infectious bronchitis coronavirus envelope protein modulates virion release, apoptosis, viral …

S Li, L Yuan, G Dai, RA Chen, DX Liu… - Frontiers in …, 2020 - frontiersin.org
Coronavirus (CoV) envelope (E) protein is a small structural protein critical for virion
morphogenesis and release. The recently characterized E protein ion channel activity (EIC) …