Immune mechanisms have been recognized to have a role in the pathogenesis of
hypertension, vascular disease and kidney damage in humans and animals for many …

Autoimmune diseases are a group of heterogeneous condition that occur secondary to the
intrinsic loss of tolerance to self-antigens. In genetically susceptible individuals, the complex …

FOXP3+ Tregs are central for the maintenance of self-tolerance and can be defective in
autoimmunity. In multiple sclerosis and type-1 diabetes, dysfunctional self-tolerance is …

Objectives To evaluate the association between long-term dietary quality, measured by the
2010 Alternative Healthy Eating Index, and risk of rheumatoid arthritis (RA) in women …

The increasing incidence in Multiple Sclerosis (MS) during the last decades in industrialized
countries might be linked to a change in dietary habits. Nowadays, enhanced salt content is …

High-salt intake is known to induce pathogenic T helper (Th) 17 cells and hypertension, but
contrary to what is known, causes hypertension only in salt-sensitive (SS) individuals. Thus …

Traditionally, arterial hypertension and subsequent end‐organ damage have been
attributed to haemodynamic factors, but increasing evidence indicates that inflammation also …

It has been demonstrated that serum/glucocorticoid regulated kinase 1 (SGK1) and the
downstream transcription factor forkhead box O1 (FoxO1) plays a critical role in the …

Today, we are facing a new era of digitization in the health care system, and with increased
access to health care information has come a growing demand for safe, cost-effective and …

Recent evidence from chemical analysis of tissue electrolyte and water composition has
shown that body Na+ content in experimental animals is not constant, does not always …