Both preclinical and clinical studies implicate functional impairments of several neuroactive
metabolites of the kynurenine pathway (KP), the major degradative cascade of the essential …

Recent studies highlight the role of brain metabolites in regulation of neuronal signals and
behaviour. To understand the underlying mechanism, brain metabolites and associated …

Cisplatin (CIS) is a potent chemotherapeutic agent primarily used to treat hematologic
malignancies and solid tumors, including lymphomas, sarcomas, and some carcinomas …

Introduction: Obesity is associated with impaired learning, but the mechanisms underlying
this cognitive dysfunction are poorly understood. Moreover, whether obesity-induced …

The high risk for anxiety and depression among individuals with stress has become a
growing concern globally. Stress-related mental disorders are often accompanied by …