Remission and recovery from first-episode psychosis in adults: systematic review and meta-analysis of long-term outcome studies

J Lally, O Ajnakina, B Stubbs, M Cullinane… - The British Journal of …, 2017 - cambridge.org
BackgroundRemission and recovery rates for people with first-episode psychosis (FEP)
remain uncertain. AimsTo assess pooled prevalence rates of remission and recovery in FEP …

Predictors of functional recovery in first-episode psychosis: a systematic review and meta-analysis of longitudinal studies

O Santesteban-Echarri, M Paino, S Rice… - Clinical psychology …, 2017 - Elsevier
Background Three out of four first-episode psychosis (FEP) patients achieve clinical
remission following treatment. Unfortunately, functional recovery lags behind symptomatic …

Recovery and serious mental illness: a review of current clinical and research paradigms and future directions

BL Leonhardt, K Huling, JA Hamm, D Roe… - Expert Review of …, 2017 - Taylor & Francis
Introduction: Recovery from serious mental illness has historically not been considered a
likely or even possible outcome. However, a range of evidence suggests the courses of SMI …

Thinking and acting beyond the positive: the role of the cognitive and negative symptoms in schizophrenia

M Carbon, CU Correll - CNS spectrums, 2014 - cambridge.org
Since currently available antipsychotic medications predominantly treat hallucinations,
delusions, disorganized thoughts and behavior, and related agitation/aggression, attention …

Clinical predictors of therapeutic response to antipsychotics in schizophrenia

M Carbon, CU Correll - Dialogues in clinical neuroscience, 2014 - Taylor & Francis
The search for clinical outcome predictors for schizophrenia is as old as the field of
psychiatry. However, despite a wealth of large, longitudinal studies into prognostic factors …

Negative symptoms of schizophrenia: clinical features, relevance to real world functioning and specificity versus other CNS disorders

G Foussias, O Agid, G Fervaha, G Remington - European …, 2014 - Elsevier
Negative symptoms have long been recognized as a central feature of the phenomenology
of schizophrenia, dating back to the early descriptions by Kraepelin and Bleuler. Over the …

Schizophrenia outcomes in the 21st century: a systematic review

P Huxley, A Krayer, R Poole, L Prendergast… - Brain and …, 2021 - Wiley Online Library
Objective We report a review of outcomes in schizophrenia in the twenty‐first century,
replicating and extending work undertaken by the late Richard Warner in his seminal …

Psychosis brain subtypes validated in first-episode cohorts and related to illness remission: results from the PHENOM consortium

DB Dwyer, GB Chand, A Pigoni, A Khuntia, J Wen… - Molecular …, 2023 - nature.com
Using machine learning, we recently decomposed the neuroanatomical heterogeneity of
established schizophrenia to discover two volumetric subgroups—a 'lower brain …

Duration of untreated illness as a key to early intervention in schizophrenia: a review

A Murru, B Carpiniello - Neuroscience letters, 2018 - Elsevier
The first psychotic episode is classically viewed as a critical period which management is
important in determining the long-term outcome of the schizophrenia (SCZ). For this reason …

Predictors of recovery in first episode psychosis: the OPUS cohort at 10 year follow-up

SF Austin, O Mors, RG Secher, CR Hjorthøj… - Schizophrenia …, 2013 - Elsevier
Background Recovery, the optimal goal in treatment, is the attainment of both symptomatic
and functional remission over a sustained period of time. Identification of factors that …