▪ Abstract Trabecular bone is a complex material with substantial heterogeneity. Its elastic
and strength properties vary widely across anatomic sites, and with aging and disease …

The tissue-level Young's modulus of trabecular bone is important for detailed mechanical
analysis of bone and bone-implant mechanical interactions. However, the heterogeneity and …

One outstanding issue regarding the relationship between elastic modulus and density for
trabecular bone is whether the relationship depends on anatomic site. To address this, on …

The ability to determine trabecular bone tissue elastic and failure properties has biological
and clinical importance. To date, trabecular tissue yield strains remain unknown due to …

There is increasing evidence that, in addition to bone mass, bone microarchitecture and its
mechanical load distribution are important factors for the determination of bone strength …

The ability to predict trabecular failure using microstructure-based computational models
would greatly facilitate study of trabecular structure–function relations, multiaxial strength …

Microcomputed tomography (microCT) has become a standard and essential tool for
quantifying structure-function relationships, disease progression, and regeneration in …

Trabecular plates and rods are important microarchitectural features in determining
mechanical properties of trabecular bone. A complete volumetric decomposition of …

In osteoarthritis, one postulate is that changes in the mechanical properties of the
subchondral bone layer result in cartilage damage. The goal of this study was to examine …

Quantitative information about bone tissue‐level loading is essential for understanding bone
mechanical behavior. We made microfinite element models of a healthy and osteoporotic …