[HTML][HTML] Omics approaches for understanding heavy metal responses and tolerance in plants

M Jamla, T Khare, S Joshi, S Patil, S Penna… - Current Plant …, 2021 - Elsevier
Recent years have witnessed a gradual increase in the bioavailability and groundwater
leaching of toxic heavy metals (HMs) in the environment, driven mainly by anthropogenic …

Common features of microRNA target prediction tools

SM Peterson, JA Thompson, ML Ufkin… - Frontiers in …, 2014 - frontiersin.org
The human genome encodes for over 1800 microRNAs (miRNAs), which are short non-
coding RNA molecules that function to regulate gene expression post-transcriptionally. Due …

mirDIP 4.1—integrative database of human microRNA target predictions

T Tokar, C Pastrello, AEM Rossos… - Nucleic acids …, 2018 - academic.oup.com
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …

[HTML][HTML] Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations

NH Alami, RB Smith, MA Carrasco, LA Williams… - Neuron, 2014 - cell.com
The RNA-binding protein TDP-43 regulates RNA metabolism at multiple levels, including
transcription, RNA splicing, and mRNA stability. TDP-43 is a major component of the …

ViennaRNA Package 2.0

R Lorenz, SH Bernhart… - Algorithms for molecular …, 2011 - Springer
Background Secondary structure forms an important intermediate level of description of
nucleic acids that encapsulates the dominating part of the folding energy, is often well …

miRecords: an integrated resource for microRNA–target interactions

F **ao, Z Zuo, G Cai, S Kang, X Gao… - Nucleic acids research, 2009 - academic.oup.com
MicroRNAs (miRNAs) are an important class of small noncoding RNAs capable of regulating
other genes' expression. Much progress has been made in computational target prediction …

A brain-specific microRNA regulates dendritic spine development

GM Schratt, F Tuebing, EA Nigh, CG Kane, ME Sabatini… - Nature, 2006 - nature.com
MicroRNAs are small, non-coding RNAs that control the translation of target messenger
RNAs, thereby regulating critical aspects of plant and animal development. In the …

Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer

S Varambally, Q Cao, RS Mani, S Shankar, X Wang… - science, 2008 - science.org
Enhancer of zeste homolog 2 (EZH2) is a mammalian histone methyltransferase that
contributes to the epigenetic silencing of target genes and regulates the survival and …

TarBase: A comprehensive database of experimentally supported animal microRNA targets

P Sethupathy, B Corda, AG Hatzigeorgiou - rna, 2006 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are~ 22-nt RNA segments that are involved in the regulation of protein
expression primarily by binding to one or more target sites on an mRNA transcript and …

Recent advances in quantum computing for drug discovery and development

G Kumar, S Yadav, A Mukherjee, V Hassija… - IEEE …, 2024 - ieeexplore.ieee.org
Preserving human health is of utmost importance, and unrestricted availability of
medications is essential for overall wellness. Pharmaceuticals, which consist of a wide …