Methods for profiling RNA and protein expression in a spatially resolved manner are rapidly
evolving, making it possible to comprehensively characterize cells and tissues in health and …

Light sheet fluorescence microscopy (LSFM) uses a thin sheet of light to excite only
fluorophores within the focal volume. Light sheet microscopes (LSMs) have a true optical …

We present LABKIT, a user-friendly Fiji plugin for the segmentation of microscopy image
data. It offers easy to use manual and automated image segmentation routines that can be …

State-of-the-art tissue-clearing methods provide subcellular-level optical access to intact
tissues from individual organs and even to some entire mammals. When combined with light …

Tissue clearing of gross anatomical samples was first described more than a century ago
and has only recently found widespread use in the field of microscopy. This renaissance has …

The cerebral vasculature is a dense network of arteries, capillaries, and veins. Quantifying
variations of the vascular organization across individuals, brain regions, or disease models …

The extraembryonic yolk sac (YS) ensures delivery of nutritional support and oxygen to the
develo** embryo but remains ill-defined in humans. We therefore assembled a …

Data security has become a paramount necessity and more obligation in daily life. Most of
our systems can be hacked, and it causes very high risks to our confidential files inside the …

Human prenatal skin is populated by innate immune cells, including macrophages, but
whether they act solely in immunity or have additional functions in morphogenesis is …

A growing community is constructing a next-generation file format (NGFF) for bioimaging to
overcome problems of scalability and heterogeneity. Organized by the Open Microscopy …