This article presents the revised consensus criteria for the diagnosis of frontotemporal
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …

Parkinson's Disease (PD) is a highly prevalent neurodegenerative disease among older
adults. PD neuropathology is marked by the progressive loss of the dopaminergic neurons …

Multiple sclerosis (MS) is an autoimmune, inflammatory neurodegenerative disease of the
central nervous system characterized by demyelination and axonal damage. Diagnosis and …

Objective To evaluate plasma phosphorylated neurofilament heavy chain (pNF‐H) as a
biomarker in spinal muscular atrophy (SMA). Methods Levels of pNF‐H were measured …

Motor neuron diseases (MNDs) are etiologically and biologically heterogeneous diseases.
The pathobiology of motor neuron degeneration is still largely unknown, and no effective …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Neurodegenerative diseases are debilitating and currently incurable conditions causing
severe cognitive and motor impairments, defined by the progressive deterioration of …

There is a need for biomarkers for amyotrophic lateral sclerosis (ALS), to support the
diagnosis of the disease, to predict disease progression and to track disease activity and …

The degeneration and dysfunction of neurons are key features of neurodegenerative
diseases (NDs). Currently, one of the main challenges facing researchers and clinicians is …

Simulation is a key tool in population genetics for both methods development and empirical
research, but producing simulations that recapitulate the main features of genomic datasets …