Development of antibiofilm therapeutics strategies to overcome antimicrobial drug resistance

S Nadar, T Khan, SG Patching, A Omri - Microorganisms, 2022 - mdpi.com
A biofilm is a community of stable microorganisms encapsulated in an extracellular matrix
produced by themselves. Many types of microorganisms that are found on living hosts or in …

Antimicrobial peptide synergies for fighting infectious diseases

JT Mhlongo, AY Waddad, F Albericio… - Advanced …, 2023 - Wiley Online Library
Antimicrobial peptides (AMPs) are essential elements of thehost defense system.
Characterized by heterogenous structures and broad‐spectrumaction, they are promising …

Our Experience over 20 years: antimicrobial peptides against gram positives, gram negatives, and fungi

G Rizzetto, D Gambini, A Maurizi, M Candelora… - Pharmaceutics, 2022 - mdpi.com
Antibiotic resistance is rapidly increasing, and new anti-infective therapies are urgently
needed. In this regard, antimicrobial peptides (AMPs) may represent potential candidates for …

Nanocarriers for combating biofilms: Advantages and challenges

Y Zhang, S Lin, J Fu, W Zhang, G Shu… - Journal of applied …, 2022 - academic.oup.com
Bacterial biofilms are highly resistant to antibiotics and pose a great threat to human and
animal health. The control and removal of bacterial biofilms have become an important topic …

Plantaricin A reverses resistance to ciprofloxacin of multidrug‐resistant Staphylococcus aureus by inhibiting efflux pumps

F Meng, T Nie, Y Lyu, F Lyu, X Bie, Y Lu… - Environmental …, 2022 - Wiley Online Library
Overexpression of Staphylococcus aureus efflux pumps is commonly associated with
antibiotic resistance, causing conventional antibiotics to be unsuccessful in combating …

Biofilm Production Ability, Virulence and Antimicrobial Resistance Genes in Staphylococcus aureus from Various Veterinary Hospitals

L Chen, ZY Tang, SY Cui, ZB Ma, H Deng, WL Kong… - Pathogens, 2020 - mdpi.com
Staphylococcus aureus (S. aureus) is one of the most clinically important zoonotic
pathogens, but an understanding of the prevalence, biofilm formulation ability, virulence …

[HTML][HTML] Natural antimicrobial agents from algae: Current advances and future directions

A Zuorro, R Lavecchia, JE Contreras-Ropero… - International Journal of …, 2024 - mdpi.com
Infectious diseases have significantly shaped human history, leading to significant
advancements in medical science. The discovery and development of antibiotics …

Temporins: Multifunctional peptides from frog skin

LD D'Andrea, A Romanelli - International Journal of Molecular Sciences, 2023 - mdpi.com
Temporins are short peptides secreted by frogs from all over the world. They exert
antimicrobial activity, mainly against Gram-positive bacteria, including resistant pathogens; …

Activity of Temporin A and Short Lipopeptides Combined with Gentamicin against Biofilm Formed by Staphylococcus aureus and Pseudomonas aeruginosa

MA Paduszynska, KE Greber, W Paduszynski… - Antibiotics, 2020 - mdpi.com
The formation of biofilms on biomaterials causes biofilm-associated infections. Available
treatments often fail to fight the microorganisms in the biofilm, creating serious risks for …

Synergistic activity of weak organic acids against uropathogens

J Burns, CP McCoy, NJ Irwin - Journal of Hospital Infection, 2021 - Elsevier
Summary Background Urinary tract infections (UTIs) are among the most common hospital-
acquired infections, with an estimated 75% of UTIs caused by urinary catheters. In addition …