Chlorogenic acids and the acyl-quinic acids: Discovery, biosynthesis, bioavailability and bioactivity

MN Clifford, IB Jaganath, IA Ludwig… - Natural product reports, 2017 - pubs.rsc.org
Covering: 2000 up to late 2017 This review is focussed upon the acyl-quinic acids, the most
studied group within the ca. 400 chlorogenic acids so far reported. The acyl-quinic acids, the …

High-confidence structural identification of metabolites relying on tandem mass spectrometry through isomeric identification: A tutorial

Y Song, Q Song, W Liu, J Li, P Tu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
MS/MS currently serves as the workhorse for metabolomics. Structural identification is
extremely important to correlate statistical variables to biochemical functions and …

Serpentine ultralong path with extended routing (SUPER) high resolution traveling wave ion mobility-MS using structures for lossless ion manipulations

L Deng, IK Webb, SVB Garimella, AM Hamid… - Analytical …, 2017 - ACS Publications
Ion mobility (IM) separations have a broad range of analytical applications, but insufficient
resolution often limits their utility. Here, we report on ion mobility separations in a structures …

ISiCLE: a quantum chemistry pipeline for establishing in silico collision cross section libraries

SM Colby, DG Thomas, JR Nuñez, DJ Baxter… - Analytical …, 2019 - ACS Publications
High-throughput, comprehensive, and confident identifications of metabolites and other
chemicals in biological and environmental samples will revolutionize our understanding of …

Ion mobility mass spectrometry for the separation and characterization of small molecules

L Liu, Z Wang, Q Zhang, Y Mei, L Li, H Liu… - Analytical …, 2023 - ACS Publications
Small molecules with molecular weights less than 1500 Da represented by natural
metabolites such as amino acids, nucleotides, carbohydrates, lipids, flavonoids, alkaloids …

Ion mobility spectrometry and the omics: Distinguishing isomers, molecular classes and contaminant ions in complex samples

KE Burnum-Johnson, X Zheng, JN Dodds, J Ash… - TrAC Trends in …, 2019 - Elsevier
Ion mobility spectrometry (IMS) is a widely used analytical technique providing rapid gas
phase separations. IMS alone is useful, but its coupling with mass spectrometry (IMS-MS) …

Deep Learning to Generate in Silico Chemical Property Libraries and Candidate Molecules for Small Molecule Identification in Complex Samples

SM Colby, JR Nuñez, NO Hodas, CD Corley… - Analytical …, 2019 - ACS Publications
Comprehensive and unambiguous identification of small molecules in complex samples will
revolutionize our understanding of the role of metabolites in biological systems. Existing and …

New mass spectrometry technologies contributing towards comprehensive and high throughput omics analyses of single cells

SP Couvillion, Y Zhu, G Nagy, JN Adkins, C Ansong… - Analyst, 2019 - pubs.rsc.org
Mass-spectrometry based omics technologies–namely proteomics, metabolomics and
lipidomics–have enabled the molecular level systems biology investigation of organisms in …

Profiling of Chlorogenic Acids from Bidens pilosa and Differentiation of Closely Related Positional Isomers with the Aid of UHPLC-QTOF-MS/MS-Based In-Source …

AT Ramabulana, P Steenkamp, N Madala, IA Dubery - Metabolites, 2020 - mdpi.com
Bidens pilosa is an edible herb from the Asteraceae family which is traditionally consumed
as a leafy vegetable. B. pilosa has many bioactivities owing to its diverse phytochemicals …

Utilizing ion mobility spectrometry and mass spectrometry for the analysis of polycyclic aromatic hydrocarbons, polychlorinated biphenyls, polybrominated diphenyl …

X Zheng, KT Dupuis, NA Aly, Y Zhou, FB Smith… - Analytica chimica …, 2018 - Elsevier
Polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs) and
polybrominated diphenyl ethers (PBDEs) are persistent environmental pollutants originating …