A narrative review on sarcopenia in type 2 diabetes mellitus: prevalence and associated factors

A Izzo, E Massimino, G Riccardi, G Della Pepa - Nutrients, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) represents a major health burden for the elderly
population, affecting approximately 25% of people over the age of 65 years. This percentage …

Branched chain amino acids, aging and age-related health

DG Le Couteur, SM Solon-Biet, VC Cogger… - Ageing research …, 2020 - Elsevier
Branched chain amino acids (BCAA: leucine, valine, isoleucine) have key physiological
roles in the regulation of protein synthesis, metabolism, food intake and aging. Many studies …

[HTML][HTML] Whey protein, leucine-and vitamin-D-enriched oral nutritional supplementation for the treatment of sarcopenia

E Cereda, R Pisati, M Rondanelli, R Caccialanza - Nutrients, 2022 - mdpi.com
Sarcopenia has been recognized as a muscle disease, with adverse consequences on
health. Updated recommendations, aimed at increasing awareness of sarcopenia and its …

[HTML][HTML] Singapore clinical practice guidelines for sarcopenia: screening, diagnosis, management and prevention

WS Lim, CY Cheong, JP Lim, MMY Tan, JQ Chia… - The Journal of frailty & …, 2022 - Elsevier
Objectives To present the local evidence and final recommendations of the Clinical Practice
Guidelines workgroup convened by the Chapter of Geriatricians and the Society for Geriatric …

Multi-omics research in sarcopenia: Current progress and future prospects

JC Liu, SS Dong, H Shen, DY Yang, BB Chen… - Ageing Research …, 2022 - Elsevier
Sarcopenia is a systemic disease with progressive and generalized skeletal muscle
dysfunction defined by age-related low muscle mass, high content of muscle slow fibers, and …

Effects of leucine administration in sarcopenia: a randomized and placebo-controlled clinical trial

FM Martínez-Arnau, R Fonfría-Vivas, C Buigues… - Nutrients, 2020 - mdpi.com
Treating sarcopenia in older individuals remains a challenge, and nutritional interventions
present promising approaches in individuals that perform limited physical exercise. We …

[HTML][HTML] The contribution of diet therapy and probiotics in the treatment of sarcopenia induced by prolonged immobilization caused by the COVID-19 pandemic

CD Nistor-Cseppento, TD Moga, AF Bungau, DM Tit… - Nutrients, 2022 - mdpi.com
The prolonged immobilization associated with COVID-19 infection and the restrictions
imposed by the pandemic have determined major changes in physical activity and eating …

Can nutrition contribute to a reduction in sarcopenia, frailty, and comorbidities in a super-aged society?

S Yoshida, R Shiraishi, Y Nakayama, Y Taira - Nutrients, 2023 - mdpi.com
Many countries are facing the advent of super-aging societies, where sarcopenia and frailty
will become pertinent problems. The prevalence of comorbidities is a major problem in …

Effects of leucine-rich protein supplements in older adults with sarcopenia: a systematic review and meta-analysis of randomized controlled trials

SY Lee, HJ Lee, JY Lim - Archives of Gerontology and Geriatrics, 2022 - Elsevier
Objectives This study examined whether leucine-rich protein supplements improve muscle
strength, mass, and performance in sarcopenic older adults. Methods We searched PubMed …

The effect of vitamin D plus protein supplementation on sarcopenia: A systematic review and meta-analysis of randomized controlled trials

NK Gkekas, P Anagnostis, V Paraschou, D Stamiris… - Maturitas, 2021 - Elsevier
Purpose The exact effect of vitamin D supplementation, either as monotherapy or in
combination with protein, on musculoskeletal health in patients with sarcopenia is currently …