NMR and metabolomics—A roadmap for the future

DS Wishart, LL Cheng, V Copié, AS Edison… - Metabolites, 2022 - mdpi.com
Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

[HTML][HTML] Metabolite discovery: Biochemistry's scientific driver

M Giera, O Yanes, G Siuzdak - Cell metabolism, 2022 - cell.com
Metabolite identification represents a major challenge, and opportunity, for biochemistry.
The collective characterization and quantification of metabolites in living organisms, with its …

NMR metabolomics methods for investigating disease

GA Nagana Gowda, D Raftery - Analytical chemistry, 2023 - ACS Publications
The field of metabolomics continues to grow exponentially as it contributes significantly to
numerous disciplines, including biomedicine, pharmacology, drug development, and …

Fingerprinting and profiling in metabolomics of biosamples

V Ghini, G Meoni, A Vignoli, F Di Cesare… - Progress in Nuclear …, 2023 - Elsevier
This review focuses on metabolomics from an NMR point of view. It attempts to cover the
broad scope of metabolomics and describes the NMR experiments that are most suitable for …

Integrative modeling of plasma metabolic and lipoprotein biomarkers of SARS-CoV-2 infection in Spanish and Australian COVID-19 patient cohorts

R Masuda, S Lodge, P Nitschke, M Spraul… - Journal of proteome …, 2021 - ACS Publications
Quantitative plasma lipoprotein and metabolite profiles were measured on an autonomous
community of the Basque Country (Spain) cohort consisting of hospitalized COVID-19 …

Integrative plasma metabolic and lipidomic modelling of SARS-CoV-2 infection in relation to clinical severity and early mortality prediction

S Lodge, NG Lawler, N Gray, R Masuda… - International Journal of …, 2023 - mdpi.com
An integrative multi-modal metabolic phenoty** model was developed to assess the
systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease …

Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in Molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

Rapid and Self-Administrable Capillary Blood Microsampling Demonstrates Statistical Equivalence with Standard Venous Collections in NMR-Based Lipoprotein …

JL Roberts, L Whiley, N Gray, M Gay… - Analytical …, 2024 - ACS Publications
We investigated plasma and serum blood derivatives from capillary blood microsamples
(500 μL, MiniCollect tubes) and corresponding venous blood (10 mL vacutainers). Samples …

Current state and future perspectives on personalized metabolomics

OP Trifonova, DL Maslov, EE Balashova, PG Lokhov - Metabolites, 2023 - mdpi.com
Metabolomics is one of the most promising 'omics' sciences for the implementation in
medicine by develo** new diagnostic tests and optimizing drug therapy. Since in …

Direct low field J-edited diffusional proton NMR spectroscopic measurement of COVID-19 inflammatory biomarkers in human serum

P Nitschke, S Lodge, D Hall, H Schaefer, M Spraul… - Analyst, 2022 - pubs.rsc.org
A JEDI NMR pulse experiment incorporating relaxational, diffusional and J-modulation peak
editing has been implemented for a low field (80 MHz proton resonance frequency) …