Data published in the last 10 years on the use of the aza-Michael reaction in organic
synthesis are described systematically. The attention is focused on environmentally friendly …

Aza-Michael reaction is a simple and accessible addition reaction performed at moderate
temperature, possibly without a catalyst and without releasing by-products. Its versatility …

Double aza-Michael addition (DAM) has become an emerging strategy for the construction
of two carbon–nitrogen bonds in a single step, which can significantly simplify the synthesis …

This comprehensive review summarizes the published literature data concerning above 1
kbar reactions for the purposes of preparative organic synthesis (more than 50 mg of the …

The organocatalysed asymmetric aza-Michael addition of hydrazones to cyclic enones has
been achieved in good yield and stereoselection using cheap and commercially available …

The unique combination of hexafluoroisopropanol (HFIP) employed as solvent and
hyperbaric conditions (10–15 kbar) allows unprecedented 1, 4-addition of poor …

Dimethyl maleate was found to be a very reactive and selective acceptor for the aza-Michael
addition in comparison to other commonly used electron-deficient alkenes. It reacts …

Novel 2, 5-meso-pyrrolidines have been straightforwardly synthesized from readily available
symmetrical double Michael acceptors. The key step rested on an aza-Michael addition of …

Efficient Brønsted acid-catalyzed aza-Michael reaction of amides and ureas with α,β-unsaturated
enones under high-pressure conditions - ScienceDirect Skip to main contentSkip to article …

The enantioselective Michael addition reaction of α‐substituted cyclic ketones with acrylates
was efficiently promoted by a primary amine chiral catalyst under high‐pressure conditions …