Mechanisms and therapeutic strategies for non‐T2 asthma

E Sze, A Bhalla, P Nair - Allergy, 2020 - Wiley Online Library
Non‐T2 asthma is traditionally defined as asthma without features of T2 asthma. The
definition is arbitrary and is generally based on the presence of neutrophils in sputum, or the …

[HTML][HTML] Breath analysis: A promising tool for disease diagnosis—the role of sensors

M Kaloumenou, E Skotadis, N Lagopati… - Sensors, 2022 - mdpi.com
Early-stage disease diagnosis is of particular importance for effective patient identification as
well as their treatment. Lack of patient compliance for the existing diagnostic methods …

[HTML][HTML] European Respiratory Society guidelines for the diagnosis of asthma in adults

R Louis, I Satia, I Ojanguren… - European …, 2022 - publications.ersnet.org
Although asthma is very common, affecting 5–10% of the population, the diagnosis of
asthma in adults remains a challenge in the real world, which results in both over-and under …

[HTML][HTML] Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD

IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …

[HTML][HTML] Treatment options in type-2 low asthma

TSC Hinks, SJ Levine… - European Respiratory …, 2021 - publications.ersnet.org
Monoclonal antibodies targeting IgE or the type-2 cytokines interleukin (IL)-4, IL-5 and IL-13
are proving highly effective in reducing exacerbations and symptoms in people with severe …

Diagnosis of COVID-19 by exhaled breath analysis using gas chromatography–mass spectrometry

W Ibrahim, RL Cordell, MJ Wilde… - ERJ open …, 2021 - publications.ersnet.org
Background The ongoing coronavirus disease 2019 (COVID-19) pandemic has claimed
over two and a half million lives worldwide so far. Severe acute respiratory syndrome …

Breathing new life into clinical testing and diagnostics: perspectives on volatile biomarkers from breath

JJ Haworth, CK Pitcher, G Ferrandino… - Critical Reviews in …, 2022 - Taylor & Francis
Human breath offers several benefits for diagnostic applications, including simple,
noninvasive collection. Breath is a rich source of clinically-relevant biological information; …

GC-MS-based metabolomics of volatile organic compounds in exhaled breath: Applications in health and disease. A review

M Bajo-Fernández, ÉA Souza-Silva… - Frontiers in Molecular …, 2024 - frontiersin.org
Exhaled breath analysis, with particular emphasis on volatile organic compounds,
represents a growing area of clinical research due to its obvious advantages over other …

Haze air pollution health impacts of breath-borne VOCs

L Zhang, X Li, H Chen, Z Wu, M Hu… - Environmental Science & …, 2022 - ACS Publications
Here, we investigated the use of breath-borne volatile organic compounds (VOCs) for rapid
monitoring of air pollution health effects on humans. Forty-seven healthy college students …

T2-“low” asthma: overview and management strategies

AM Fitzpatrick, BE Chipps, F Holguin… - The Journal of Allergy and …, 2020 - Elsevier
Although the term “asthma” has been applied to all patients with airway lability and variable
chest symptoms for centuries, phenotypes of asthma with distinct clinical and molecular …