ABSTRACT Carbon/nitrogen (C/N) balance sensing is a key requirement for the
maintenance of cellular homeostasis. Therefore, cyanobacteria have evolved a …

Highlights●Why biofuels and bioproducts remain critical to society●What molecular
products can be made by biotechnology using available feedstocks●How new systems and …

Ocean microbes drive biogeochemical cycling on a global scale. However, this cycling is
constrained by viruses that affect community composition, metabolic activity, and …

PII proteins are multitasking information-processing proteins occurring in bacteria, archaea,
and plastids, decoding the metabolic state of the cells and providing this information to …

For organisms to coordinate their growth and development with nutrient availability, they
must be able to sense nutrient levels in their environment. Here, we review select nutrient …

The metabolite 2-oxoglutarate (also known as α-ketoglutarate, 2-ketoglutaric acid, or
oxoglutaric acid) lies at the intersection between the carbon and nitrogen metabolic …

Glutamine (Gln) is the first amino acid synthesized in nitrogen (N) assimilation in plants. Gln
synthetase (GS), converting glutamate (Glu) and NH4+ into Gln at the expense of ATP, is …

Carbon and nitrogen are the two most abundant nutrient elements for all living organisms,
and their metabolism is tightly coupled. What are the signaling mechanisms that cells use to …

We present a comprehensive overview of the hierarchical network of intracellular processes
revolving around central nitrogen metabolism in Escherichia coli. The hierarchy intertwines …

Ammonia-oxidizing archaea (AOA) are among the most abundant microorganisms and key
players in the global nitrogen and carbon cycles. They share a common energy metabolism …