Free radicals are chemical species (atoms, molecules, or ions) containing one or more
unpaired electrons in their external orbitals and generally display a remarkable reactivity …

Deinococcus radiodurans is a robust bacterium best known for its capacity to repair massive
DNA damage efficiently and accurately. It is extremely resistant to many DNA-damaging …

Life evolved in an anaerobic world; therefore, fundamental enzymatic mechanisms and
biochemical pathways were refined and integrated into metabolism in the absence of any …

Uncovers the Key Role Microbes Play in the Transformation of Oxidizable and Reducible
MineralsMany areas of geomicrobial processes are receiving serious attention from …

The first bacterial genome was sequenced in 1995, and the first archaeal genome in 1996.
Soon after these breakthroughs, an exponential rate of genome sequencing was …

Deinococcus bacteria are famous for their extreme resistance to ionising radiation and other
DNA damage-and oxidative stress-generating agents. More than a hundred genes have …

Approximately one third of the human proteome contains metal cations, either in the form of
cofactors with catalytic functions or as structural support elements. 1, 2 To guarantee a …

A variety of reactive oxygen species react readily with methionine residues in proteins to
form methionine sulfoxide, thus scavenging the reactive species. Most cells contain …

In classical models of radiation toxicity, DNA is the molecule that is most affected by ionizing
radiation (IR). However, recent data show that the amount of protein damage caused during …

The redox-active metal manganese plays a key role in cellular adaptation to oxidative stress.
As a cofactor for manganese superoxide dismutase or through formation of non …