Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …

Oxidative stress (OS) has the ability to damage different molecules and cellular structures,
altering the correct function of organs and systems. OS accumulates in the body by …

While the elderly segment of the population continues growing in importance,
neurodegenerative diseases increase exponentially. Lifestyle factors such as nutrition …

Oxidative stress is induced by an imbalanced redox states, involving either excessive
generation of reactive oxygen species (ROS) or dysfunction of the antioxidant system. The …

Despite extensive research, the current theories on serotonergic dysfunctions and cortisol
hypersecretion do not provide sufficient explanations for the nature of depression. Rational …

Introduction• Protein aggregation‐'Toxic oligomer'hypothesis‐Protein (mis) folding‐
Proteostasis and molecular chaperones‐Protein misfolding and endoplasmic reticulum …

There is increasing awareness of the ubiquitous role of oxidative stress in
neurodegenerative disease states. A continuing challenge is to be able to distinguish …

Lipid peroxidation is a complex process involving the interaction of oxygen-derived free
radicals with polyunsaturated fatty acids, resulting in a variety of highly reactive electrophilic …

Background Memory and cognitive impairments/disorders are the main clinical symptoms of
neurodegenerative diseases. The prevalence of such chronic conditions has increased over …

Parkinson's disease (PD) is a neurodegenerative disorder that alters either motor or non-
motor activities. Dopamine-based medications can help alleviate symptoms at an early …