PIWI-interacting RNAs: small RNAs with big functions
In animals, PIWI-interacting RNAs (piRNAs) of 21–35 nucleotides in length silence
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
transposable elements, regulate gene expression and fight viral infection. piRNAs guide …
piRNA-guided genome defense: from biogenesis to silencing
PIWI-interacting RNAs (piRNAs) and their associated PIWI clade Argonaute proteins
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
constitute the core of the piRNA pathway. In gonadal cells, this conserved pathway is crucial …
Mosquito vector competence for dengue is modulated by insect-specific viruses
Aedes aegypti and A. albopictus mosquitoes are the main vectors for dengue virus (DENV)
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …
and other arboviruses, including Zika virus (ZIKV). Understanding the factors that affect …
Small RNA-based antimicrobial immunity
Protection against microbial infection in eukaryotes is provided by diverse cellular and
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
molecular mechanisms. Here, we present a comparative view of the antiviral activity of virus …
Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the …
Vector biology meets disease control: using basic research to fight vector-borne diseases
WR Shaw, F Catteruccia - Nature microbiology, 2019 - nature.com
Human pathogens that are transmitted by insects are a global problem, particularly those
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
vectored by mosquitoes; for example, malaria parasites transmitted by Anopheles species …
Host–transposon interactions: conflict, cooperation, and cooption
Transposable elements (TEs) are mobile DNA sequences that colonize genomes and
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
threaten genome integrity. As a result, several mechanisms appear to have emerged during …
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence against transposable elements
In animals, small RNA molecules termed PIWI-interacting RNAs (piRNAs) silence
transposable elements (TEs), protecting the germline from genomic instability and mutation …
transposable elements (TEs), protecting the germline from genomic instability and mutation …
Origins and diversification of animal innate immune responses against viral infections
Immune systems are of pivotal importance to any living organism on Earth, as they protect
the organism against deleterious effects of viral infections. Though the current knowledge …
the organism against deleterious effects of viral infections. Though the current knowledge …
Insect antiviral innate immunity: pathways, effectors, and connections
MB Kingsolver, Z Huang, RW Hardy - Journal of molecular biology, 2013 - Elsevier
Insects are infected by a wide array of viruses some of which are insect restricted and
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …
pathogenic, and some of which are transmitted by biting insects to vertebrates. The medical …