The roles of long non-coding RNAs in ovarian cancer: from functions to therapeutic implications

Z Hu, L Yuan, X Yang, C Yi, J Lu - Frontiers in Oncology, 2024 - pmc.ncbi.nlm.nih.gov
Long non-coding RNAs (lncRNAs) are multifunctional and participate in a variety of
biological processes and gene regulatory networks. The deregulation of lncRNAs has been …

Emerging therapeutic targets for retinoblastoma

R Manukonda, RVL Narayana, S Kaliki… - Expert Opinion on …, 2022 - Taylor & Francis
ABSTRACT Introduction Retinoblastoma (Rb) is an early childhood intraocular tumor of the
retina and is managed by multimodal therapeutic approaches. Recent advanced targeted …

[HTML][HTML] Small extracellular vesicles loaded with carboplatin effectively enhance the cytotoxicity of drug-resistant cells from Y79 cells-in vitro

J Attem, RVL Narayana, R Manukonda, S Kaliki… - Biomedicine & …, 2024 - Elsevier
Drug resistance (DR) is one of the challenges in treating retinoblastoma (Rb) that warrants
novel approaches. With the emerging evidence on the role of small extracellular vesicles …

CD63/81 small extracellular vesicles in the aqueous humor are retinoblastoma associated

S Pike, CC Peng, P Neviani… - … ophthalmology & visual …, 2023 - iovs.arvojournals.org
Purpose: Although biopsy is contraindicated in retinoblastoma (RB), the aqueous humor
(AH) is a robust liquid biopsy source of molecular tumor information, facilitating biomarker …

The Role of Small Extracellular Vesicles in Retinoblastoma Development and Progression

J Attem, GK Vemuganti - Current Eye Research, 2025 - Taylor & Francis
A growing body of research on extracellular vesicles (EVs) in cancer has revealed their
novel and crucial activities in the progression of tumors while also paving the way for …

[HTML][HTML] Identifying treatment resistance related pathways by analyzing serum extracellular vesicles of patients with resistant versus regressed retinoblastoma

R Manukonda, S Jakati, J Attem… - … & visual science, 2023 - jov.arvojournals.org
Purpose: To identify the genes and pathways responsible for treatment resistance (TR) in
retinoblastoma (RB) by analyzing serum small extracellular vesicles (sEVs) of patients with …

Liquid biopsy: current status and future perspectives

V Baev, D Koppers-Lalic, B Costa-Silva - Cancers, 2023 - mdpi.com
Since the discovery of the Bence Jones protein in the middle to late 1800s and the
subsequent identification of the carcinoembryonic antigen and alpha-fetoprotein in the …

The enigmatic world of tear extracellular vesicles (EVs)–exploring their role in ocular health and beyond

A Fatima, S Sanyal, GK Jha, S Kaliki, R Pallavi - FEBS letters - Wiley Online Library
Extracellular vesicles (EVs) are released by all kind of cells into the extracellular space,
where they shuttle parental cell‐derived molecular cargoes (DNA, RNA, proteins) to both …