HSP90 and co-chaperones: impact on tumor progression and prospects for molecular-targeted cancer therapy

A Jafari, M Rezaei-Tavirani… - Cancer …, 2020 - Taylor & Francis
Abstract Heat shock protein 90 (HSP90), a highly and unique chaperone, presents as a
double-edged sword. It plays an essential role in many physiological and pathological …

Marine biome-derived secondary metabolites, a class of promising antineoplastic agents: A systematic review on their classification, mechanism of action and future …

A Sugumaran, R Pandiyan, P Kandasamy… - Science of The Total …, 2022 - Elsevier
Cancer is one of the most deadly diseases on the planet. Over the past decades, numerous
antineoplastic compounds have been discovered from natural resources such as medicinal …

Moroccan medicinal plants used to treat cancer: ethnomedicinal study and insights into pharmacological evidence

N El Hachlafi, N Benkhaira, M Ferioun… - Evidence‐Based …, 2022 - Wiley Online Library
Cancer is one of the major medical challenges, with an unacceptably high death toll
worldwide. In Morocco, medicinal plants continue to play a pivotal therapeutic role despite …

Exploring the Anticancer Potential of Semisynthetic Derivatives of 7α-Acetoxy-6β-hydroxyroyleanone from Plectranthus sp.: An In Silico Approach

A Merecz-Sadowska, VMS Isca, P Sitarek… - International Journal of …, 2024 - mdpi.com
The diterpene 7α-acetoxy-6β-hydroxyroyleanone isolated from Plectranthus grandidentatus
demonstrates promising antibacterial, anti-inflammatory and anticancer properties …

RP-HPLC method development, validation, and drug repurposing of sofosbuvir pharmaceutical dosage form: a multidimensional study

GR Mangrio, A Maneengam, Z Khalid, TH Jafar… - Environmental …, 2022 - Elsevier
A smooth, exceptionally sensitive, correct, and extra reproducible RP-HPLC technique was
developed and demonstrated to estimate Sofosbuvir (SOF) in pharmaceutical dosage …

Network pharmacology integrated with molecular docking reveals the anticancer mechanism of Jasminum sambac Linn. essential oil against human breast cancer …

SG Lakshmi, M Kamaraj, TG Nithya… - Applied Biochemistry …, 2024 - Springer
Jasminum sambac L.(J. sambac) belongs to the family Oleaceae and it is an ornamental
subtropical evergreen shrub used in traditional treatments of certain ailments and diseases …

[HTML][HTML] UPLC-QTOF-MS/MS driven network pharmacology approach for elucidating antiproliferative pharmacological mechanisms of Plumbago zeylanica L.

BD Gupta, A Kar, S Gayen, S Jana, S Sarkar… - Industrial Crops and …, 2025 - Elsevier
Medicinal plants and derived products are alternative sources of lead compounds for the
management of different ailments, including cancer and allied diseases. Plumbago …

Screening and characterization of phytochemical content of methanolic extract of Rhizome of Curcuma amada and their antibacterial activity against MRSA

R Mahadevi, SH Salmen, S Alfarraj, M Wainwright… - Applied …, 2021 - Springer
The purpose of this study was to assess the phytochemical profile and antibacterial
competence of Curcuma amada rhizome extract against methicillin-resistant Staphylococcus …

[PDF][PDF] Study to elucidate the inhibitory potential of selected flavonoids against Jab1 in cervical cancer

P Maurya, P Pandey, F Khan, R Mishra… - Biointerface Res Appl …, 2022 - researchgate.net
Jab1 has gained tremendous attention as a potent target in cancer therapeutics. Jab1 has
been associated with the progression of numerous carcinomas by exhibiting several …

Establishment of the tandem mass spectrometric fingerprints of taxane‐based anticancer compounds

A Khajavinia, A Haddadi… - Rapid Communications in …, 2021 - Wiley Online Library
Rationale Compounds in the taxane drug family are among the most successful and
effective chemotherapeutic agents used in the treatment of solid tumors, such as breast …