Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

Hypervalent aryliodoumiums are intensively investigated as arylating agents. They are
excellent surrogates to aryl halides, and moreover they exhibit better reactivity, which allows …

The chemistry of nitrogen-containing heterocyclic compound pyrrole and pyrrolidine has
been a versatile field of study for a long time for its diverse biological and medicinal …

A chiral phosphine oxide-ligated Ni–Al bimetallic catalyst was used to realize an
enantioselective C2–H alkylation of pyridines without the need of a C2-block. A wide range …

Heterocyclic compounds are a class of compounds of natural origin with favorable
properties and hence have major pharmaceutical significance. They have an exceptional …

Abstract Since its discovery 1, 2, 4-triazole ring has emerged as a prominent heterocyclic
scaffold in medicinal chemistry. It possesses a wide spectrum of biological activities such as …

Pyrazole and its derivatives are considered a privileged N-heterocycle with immense
therapeutic potential. Over the last few decades, the pot, atom, and step economy (PASE) …

As the incorporation of heterocycles increases the physical characteristics and biological
activity of pharmacological molecules, heterocyclic scaffolds are commonly discovered as …

With the significant increase of patients suffering from different types of cancer, it is evident
that prompt measures in the development of novel and effective agents need to be taken …

Alzheimer's disease (AD) is a detrimental neurodegenerative disease that progressively
worsens with time. Clinical options are limited and only provide symptomatic relief to AD …