Polymeric Nanoparticles for Drug Delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Polysaccharide-based nanocarriers for efficient transvascular drug delivery

M Zhang, H Ma, X Wang, B Yu, H Cong… - Journal of Controlled …, 2023 - Elsevier
Polysaccharide-based nanocarriers (PBNs) are the focus of extensive investigation because
of their biocompatibility, low cost, wide availability, and chemical versatility, which allow a …

Reregulated mitochondrial dysfunction reverses cisplatin resistance microenvironment in colorectal cancer

Y Wang, X Ma, W Zhou, C Liu, H Zhang - Smart Medicine, 2022 - Wiley Online Library
Chemotherapy is one of the most basic and important treatments for malignant tumors.
However, most chemotherapeutic drugs suffer from the resistance of tumor cells and lead to …

[HTML][HTML] Recent advances in access to overcome cancer drug resistance by nanocarrier drug delivery system

X Sun, P Zhao, J Lin, K Chen, J Shen - Cancer Drug Resistance, 2023 - ncbi.nlm.nih.gov
Cancer is currently one of the most intractable diseases causing human death. Although the
prognosis of tumor patients has been improved to a certain extent through various modern …

Nanotheranostics for image-guided cancer treatment

IS Dennahy, Z Han, WM MacCuaig, HM Chalfant… - Pharmaceutics, 2022 - mdpi.com
Image-guided nanotheranostics have the potential to represent a new paradigm in the
treatment of cancer. Recent developments in modern imaging and nanoparticle design offer …

Targeted Cyclo [8] pyrrole-Based NIR-II Photoacoustic Tomography Probe for Suppression of Orthotopic Pancreatic Tumor Growth and Intra-abdominal Metastases

J Chen, R Chen, CV Chau, AC Sedgwick… - Journal of the …, 2024 - ACS Publications
Pancreatic cancer is highly lethal. New diagnostic and treatment modalities are desperately
needed. We report here that an expanded porphyrin, cyclo [8] pyrrole (CP), with a high …

Perfluoropentane/apatinib-encapsulated metal–organic framework nanoparticles enhanced the microwave ablation of hepatocellular carcinoma

D Zhang, Y Zhang, Y Luo, E Qi, J Yu, P Liang - Nanoscale Advances, 2023 - pubs.rsc.org
Microwave ablation (MWA) is a promising minimally invasive therapy for hepatocellular
carcinoma (HCC). However, the efficiency of MWA in treating HCC is evidently limited by the …

Theranostic nanoparticles for detection and treatment of pancreatic cancer

H Agarwal, RC Bynum, N Saleh… - Wiley …, 2024 - Wiley Online Library
Pancreatic ductal adenocarcinoma (PDAC) is one of the most recalcitrant cancers due to its
late diagnosis, poor therapeutic response, and highly heterogeneous microenvironment …

Toxicity assessment of mesoporous silica nanoparticles upon intravenous injection in mice: implications for drug delivery

WM MacCuaig, A Samykutty, J Foote, W Luo… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles are popular tools utilized to selectively deliver drugs and contrast agents for
identification and treatment of disease. To determine the usefulness and translational …

Biopolymer-Based Nanomedicine for Cancer Therapy: Opportunities and Challenges

X Wu, Y **n, H Zhang, L Quan, Q Ao - International Journal of …, 2024 - Taylor & Francis
Cancer, as the foremost challenge among human diseases, has plagued medical
professionals for many years. While there have been numerous treatment approaches in …