Based on the enhanced permeability and retention (EPR) effect, nanoparticles are believed
to accumulate in tumors. In this conjunction, the stability of drug encapsulation is assumed to …

To develop an injectable formulation and improve the stability of disulfiram (DSF), DSF was
encapsulated into mixed nanoparticles (DSF-NPs) through a high-pressure homogenization …

Paclitaxel (PTX)-loaded liposomes were developed with the goal of enhancing the effects of
cancer treatment. Although loading substances into the lipid membrane of liposome cause …

Liver cancer is a leading cause of death related to cancer worldwide. Poly (dl-lactide-co-
glycolide)(PLGA) nanoparticles provide prolonged blood residence time and sustained drug …

The objective of the present study was to develop self micro emulsifying formulation (SMEF)
of valsartan to improve its oral bioavailability. The formulations were screened on the basis …

Enzyme therapy is an effective strategy to treat diseases. Three strategies were pursued to
provide the favorable microenvironments for uricase (UCU) to eventually improve its …

In an attempt to improve the localized paclitaxel delivery, carrier based thermoresponsive
chitosan hydrogel was exploited in the present study. Nanoliposomes as carrier for …

Enzyme therapy has unique advantages over traditional chemotherapies for the treatment of
hyperuricemia, but overcoming the delivery obstacles of therapeutic enzymes is still a …

Taxanes introduction in the mid 90s leads to significant advancement as well as superlative
improvement in the treatment of cancer. Since then, several strategies have been designed …

Purpose To propose a novel composite nanoemulsion formulation that contains no
surfactant, but offers great stability and improved oral absorption capabilities. Methods The …