Toxoplasma gondii infection and its implications within the central nervous system

SK Matta, N Rinkenberger, IR Dunay… - Nature Reviews …, 2021 - nature.com
Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

Infectious immunity in the central nervous system and brain function

RS Klein, C Garber, N Howard - Nature immunology, 2017 - nature.com
Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

Advances and challenges in understanding cerebral toxoplasmosis

D Schlüter, A Barragan - Frontiers in immunology, 2019 - frontiersin.org
Toxoplasma gondii is a widespread parasitic pathogen that infects over one third of the
global human population. The parasite invades and chronically persists in the central …

[PDF][PDF] Global status of Toxoplasma gondii infection: systematic review and prevalence snapshots.

A Molan, K Nosaka, M Hunter, W Wang - 2019 - msptm.org
Our group sought to determine the global status of T. gondii infection and to evaluate any
continental and geographical trends by systematically examining the currently available …

Impact of environmental factors on the emergence, transmission and distribution of Toxoplasma gondii

C Yan, LJ Liang, KY Zheng, XQ Zhu - Parasites & vectors, 2016 - Springer
Toxoplasma gondii is an obligate intracellular protozoan that poses a great threat to human
health and economic well-being worldwide. The effects of environmental factors such as …

Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort

K Sugden, TE Moffitt, L Pinto, R Poulton, BS Williams… - PLoS …, 2016 - journals.plos.org
Background Toxoplasma gondii (T. gondii) is a protozoan parasite present in around a third
of the human population. Infected individuals are commonly asymptomatic, though recent …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
develo** low‐cost vaccines to prevent infectious disease outbreaks and epidemics …

Cryo-EM structure of cortical microtubules from human parasite Toxoplasma gondii identifies their microtubule inner proteins

X Wang, Y Fu, WL Beatty, M Ma, A Brown… - Nature …, 2021 - nature.com
In living cells, microtubules (MTs) play pleiotropic roles, which require very different
mechanical properties. Unlike the dynamic MTs found in the cytoplasm of metazoan cells …

MicroRNAs: biological regulators in pathogen–host interactions

SM Acuna, LM Floeter-Winter, SM Muxel - Cells, 2020 - mdpi.com
An inflammatory response is essential for combating invading pathogens. Several effector
components, as well as immune cell populations, are involved in mounting an immune …

[HTML][HTML] Toxoplasmosis in Germany: epidemiology, diagnosis, risk factors, and treatment

U Pleyer, U Gross, D Schlüter, H Wilking… - Deutsches Ärzteblatt …, 2019 - ncbi.nlm.nih.gov
Background With approximately 30% of the world population infected, Toxoplasma gondii is
one of the most widespread pathogenic parasites in both humans and animals and a major …