The insulin-degrading enzyme (IDE) is a Zn2+ peptidase originally discovered as the main
enzyme involved in the degradation of insulin and other amyloidogenic peptides, such as …

Insulin-degrading enzyme (IDE) is a multifunctional protease due to the variety of its
substrates, its various cellular locations, its conservation between species and its many non …

Insulin resistance is a salient player in the pathogenesis of obesity and its related abnormal
glucose-insulin homeostasis. Red rice bran extract (RRBE) demonstrates several bioactive …

Aim To investigate the use of synthetic preimplantation factor (sPIF) as a potential
therapeutic tool for improving glucose‐stimulated insulin secretion (GSIS), glucose tolerance …

SIRT3 deacetylates mitochondrial proteins, thereby enhancing their function. We have
previously demonstrated that Sirt3 gene deletion leads to brain mitochondrial dysfunction …

β-Amyloid peptide (Aβ) deposition in the brain is an important pathological change in
Alzheimer's disease (AD). Insulin-degrading enzyme (IDE), which is regulated …

Maternal overnutrition has been reported to affect brain plasticity of the offspring by altering
gene expression, regulating both synaptic plasticity and adult neurogenesis. However …

Background Fasting has been widely used to improve various metabolic diseases in
humans. Adaptive fasting is necessary for metabolic adaptation during prolonged fasting …

Scope Long‐term high‐fat diet (HFD) causes insulin resistance, which is a primary
etiological factor in the development of obesity and type 2 diabetes mellitus. Impaired insulin …

Marine algae have emerged as good alternative source of medical, pharmaceutical, and
food industries, it's used for anticancer, anti-inflammatory, antioxidant, antimicrobial, etc., In …