Malignant gliomas in adults
Malignant gliomas, the most common type of primary brain tumor in adults, are associated
with disproportionate cancer-related morbidity and mortality. Recently, there have been …
with disproportionate cancer-related morbidity and mortality. Recently, there have been …
[HTML][HTML] Abscisic acid synthesis and response
R Finkelstein - The Arabidopsis book/American society of plant …, 2013 - ncbi.nlm.nih.gov
Abscisic acid (ABA) is one of the “classical” plant hormones, ie discovered at least 50 years
ago, that regulates many aspects of plant growth and development. This chapter reviews our …
ago, that regulates many aspects of plant growth and development. This chapter reviews our …
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
Summary The Cancer Genome Atlas Network recently cataloged recurrent genomic
abnormalities in glioblastoma multiforme (GBM). We describe a robust gene expression …
abnormalities in glioblastoma multiforme (GBM). We describe a robust gene expression …
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 …
M Weller, N Butowski, DD Tran, LD Recht, M Lim… - The lancet …, 2017 - thelancet.com
Background Rindopepimut (also known as CDX-110), a vaccine targeting the EGFR
deletion mutation EGFRvIII, consists of an EGFRvIII-specific peptide conjugated to keyhole …
deletion mutation EGFRvIII, consists of an EGFRvIII-specific peptide conjugated to keyhole …
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year …
Background In 2004, a randomised phase III trial by the European Organisation for
Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada …
Research and Treatment of Cancer (EORTC) and National Cancer Institute of Canada …
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp, WP Mason, MJ Van Den Bent… - New England journal …, 2005 - Mass Medical Soc
Background Glioblastoma, the most common primary brain tumor in adults, is usually rapidly
fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to …
fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to …
Springer series in statistics
The idea for this book came from the time the authors spent at the Statistics and Applied
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …
Mathematical Sciences Institute (SAMSI) in Research Triangle Park in North Carolina …
Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials.
L Gaspar, C Scott, M Rotman, S Asbell… - … journal of radiation …, 1997 - europepmc.org
Purpose Promising results from new approaches such as radiosurgery or stereotactic
surgery of brain metastases have recently been reported. Are these results due to the …
surgery of brain metastases have recently been reported. Are these results due to the …
First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma
LM Liau, K Ashkan, DD Tran, JL Campian… - Journal of translational …, 2018 - Springer
Background Standard therapy for glioblastoma includes surgery, radiotherapy, and
temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate …
temozolomide. This Phase 3 trial evaluates the addition of an autologous tumor lysate …
Glioblastoma multiforme: Pathogenesis and treatment
Abstract Each year, about 5–6 cases out of 100,000 people are diagnosed with primary
malignant brain tumors, of which about 80% are malignant gliomas (MGs). Glioblastoma …
malignant brain tumors, of which about 80% are malignant gliomas (MGs). Glioblastoma …