The role of astrocytes in CNS inflammation

F Giovannoni, FJ Quintana - Trends in immunology, 2020 - cell.com
Astrocytes are the most abundant cell type in the central nervous system (CNS), performing
complex functions in health and disease. It is now clear that multiple astrocyte subsets or …

Beyond the GFAP-astrocyte protein markers in the brain

AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Astrocytic modulation of blood brain barrier: perspectives on Parkinson's disease

R Cabezas, M Ávila, J Gonzalez… - Frontiers in cellular …, 2014 - frontiersin.org
The blood–brain barrier (BBB) is a tightly regulated interface in the Central Nervous System
(CNS) that regulates the exchange of molecules in and out from the brain thus maintaining …

A literature review of traumatic brain injury biomarkers

HS Ghaith, AA Nawar, MD Gabra… - Molecular …, 2022 - Springer
Research into TBI biomarkers has accelerated rapidly in the past decade owing to the
heterogeneous nature of TBI pathologies and management, which pose challenges to TBI …

[HTML][HTML] Neurosteroids as regulators of neuroinflammation

C Yilmaz, K Karali, G Fodelianaki, A Gravanis… - Frontiers in …, 2019 - Elsevier
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …

Sex differences in neurodevelopmental and neurodegenerative disorders: focus on microglial function and neuroinflammation during development

R Hanamsagar, SD Bilbo - The Journal of steroid biochemistry and …, 2016 - Elsevier
Several neurological conditions are associated with sex differences in prevalence or
outcome. For example, autism predominantly affects boys, depression is more common in …

Tissue physiology and pathology of aromatase

C Stocco - Steroids, 2012 - Elsevier
Aromatase is expressed in multiple tissues, indicating a crucial role for locally produced
oestrogens in the differentiation, regulation and normal function of several organs and …

Alzheimer's genes in microglia: a risk worth investigating

A Sudwarts, G Thinakaran - Molecular neurodegeneration, 2023 - Springer
Despite expressing many key risk genes, the role of microglia in late-onset Alzheimer's
disease pathophysiology is somewhat ambiguous, with various phenotypes reported to be …

[HTML][HTML] Lower urinary tract symptoms in depression: a review

DJ Anderson, A Aucoin, CR Toups… - Health psychology …, 2023 - ncbi.nlm.nih.gov
Abstract Lower Urinary Tract Symptoms (LUTS) are frequently present in the general
population as patients age with approximately a third of individuals experiencing LUTS …

Contributions of sex to cerebrovascular function and pathology

LS Robison, OJ Gannon, AE Salinero, KL Zuloaga - Brain research, 2019 - Elsevier
Sex differences exist in how cerebral blood vessels function under both physiological and
pathological conditions, contributing to observed sex differences in risk and outcomes of …