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The stressed synapse 2.0: pathophysiological mechanisms in stress-related neuropsychiatric disorders
Stress is a primary risk factor for several neuropsychiatric disorders. Evidence from
preclinical models and clinical studies of depression have revealed an array of structural …
preclinical models and clinical studies of depression have revealed an array of structural …
[HTML][HTML] Laboratory models of post-traumatic stress disorder: The elusive bridge to translation
Post-traumatic stress disorder (PTSD) is a debilitating mental illness composed of a
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
heterogeneous collection of symptom clusters. The unique nature of PTSD as arising from a …
Stress, microRNAs, and stress-related psychiatric disorders: an overview
Stress is a major risk factor for psychiatric disorders. During and after exposure to stressors,
the stress response may have pro-or maladaptive consequences, depending on several …
the stress response may have pro-or maladaptive consequences, depending on several …
Understanding mechanistic aspect of the therapeutic role of herbal agents on neuroplasticity in cerebral ischemic-reperfusion injury
A Bangar, H Khan, A Kaur, K Dua, TG Singh - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Stroke is one of the leading causes of death and disability.
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …
The only FDA-approved therapy for treating stroke is tissue plasminogen activator (tPA) …
Changes in the serum concentration levels of serotonin, tryptophan and cortisol among stress-resilient and stress-susceptible individuals after experiencing traumatic …
EA Ogłodek - International Journal of Environmental Research and …, 2022 - mdpi.com
Background: Stress is a common response to many environmental adversities. However,
once dysregulated, this reaction can lead to psychiatric illnesses, such as post-traumatic …
once dysregulated, this reaction can lead to psychiatric illnesses, such as post-traumatic …
[HTML][HTML] Epigenetic mechanisms impacted by chronic stress across the rodent lifespan
A Dion, PT Muñoz, TB Franklin - Neurobiology of Stress, 2022 - Elsevier
Exposures to stress at all stages of development can lead to long-term behavioural effects,
in part through changes in the epigenome. This review describes rodent research …
in part through changes in the epigenome. This review describes rodent research …
[HTML][HTML] MicroRNAs in learning and memory and their impact on Alzheimer's disease
IF Wang, PC Ho, KJ Tsai - Biomedicines, 2022 - mdpi.com
Learning and memory formation rely on the precise spatiotemporal regulation of gene
expression, such as microRNA (miRNA)-associated silencing, to fine-tune gene expression …
expression, such as microRNA (miRNA)-associated silencing, to fine-tune gene expression …
Orbitofrontal cortex microRNAs support long-lasting heroin seeking behavior in male rats
Recovery from opioid use disorder (OUD) and maintenance of abstinence from opioid use is
hampered by perseverant drug cravings that may persist for months after cessation of drug …
hampered by perseverant drug cravings that may persist for months after cessation of drug …
[HTML][HTML] Dysregulation of miR-15a-5p, miR-497a-5p and miR-511-5p is associated with modulation of BDNF and FKBP5 in brain areas of PTSD-related susceptible …
OM Maurel, SA Torrisi, C Barbagallo… - International journal of …, 2021 - mdpi.com
Post-traumatic stress disorder (PTSD) is a neuropsychiatric disorder occurring in susceptible
individuals following a traumatic event. Understanding the mechanisms subserving trauma …
individuals following a traumatic event. Understanding the mechanisms subserving trauma …
Sex differences in acute early life stress‐enhanced fear learning in adult rats
BL Minshall, RA Skipper, CA Riddle… - Developmental …, 2024 - Wiley Online Library
Patients diagnosed with posttraumatic stress disorder (PTSD) present with a spectrum of
debilitating anxiety symptoms resulting from exposure to trauma. Women are twice as likely …
debilitating anxiety symptoms resulting from exposure to trauma. Women are twice as likely …