The syndemics model of health focuses on the biosocial complex, which consists of
interacting, co-present, or sequential diseases and the social and environmental factors that …

Gene therapy has historically been defined as the addition of new genes to human cells.
However, the recent advent of genome-editing technologies has enabled a new paradigm in …

Bacterial culture was the first method used to describe the human microbiota, but this
method is considered outdated by many researchers. Metagenomics studies have since …

Persisters are transiently tolerant variants that allow populations to avoid eradication by
antibiotic treatment. Their antibiotic tolerance is non-genetic, not inheritable and results from …

Bacteriophages are viruses that infect bacteria. In this perspective, we discuss several
aspects of a characteristic feature of bacteriophages, their host range. Each phage has its …

Since the 1940s, Staphylococcus aureus has adapted to the use of different antimicrobials to
treat infections. Although S. aureus can act as a commensal bacterium, some strains are …

Bacteria are central to human health and disease, but existing tools to edit microbial
consortia are limited. For example, broad-spectrum antibiotics are unable to precisely …

ABSTRACT CRISPR (clustered regularly interspaced short palindromic repeats)-Cas
(CRISPR-associated) systems in bacteria and archaea employ CRISPR RNAs to specifically …

The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Staphylococcus aureus is one of the most common pathogens of humans and animals,
where it frequently colonizes skin and mucosal membranes. It is of major clinical importance …