Nanopore-based sensors typically work by monitoring transient pulses in conductance via
current–time traces as molecules translocate through the nanopore. The unique property of …

The advent of single-molecule probing techniques has revolutionized the biomedical and
life science fields and has spurred the development of a new class of labs-on-chip based on …

Experimental techniques to monitor and visualize the behaviors of single nanoparticles have
not only revealed the significant spatial and temporal heterogeneity of those individuals …

Delivery of molecules into intracellular compartments is one of the fundamental
requirements in molecular biology. However, the possibility of delivering a precise number …

Nonlinear field dependence of electrophoresis in high fields has been investigated
theoretically, yet experimental studies have failed to reach consensus on the effect. In this …

Extracellular vesicles (EVs) are cell-derived, naturally produced, membrane-bound
nanoscale particles that are linked to cell-cell communication and the propagation of …

Single‐molecule nanopore detection technology has revolutionized proteomics research by
enabling highly sensitive and label‐free detection of individual proteins. Herein, we …

The development of optical imaging techniques has led to significant advancements in
single‐nanoparticle tracking and analysis, but these techniques are incapable of label‐free …

Here, we present an experimental demonstration of slowing DNA translocation across a
nanochannel by modulating the channel surface charge through an externally applied gate …

Electrical detection of single molecule based on solid‐state nanopores is recently combined
with optical methods. The synergistic effect of the electrical and optical measurements …