Interactions between the nervous and immune systems were recognized long ago, but
recent studies show that this crosstalk occurs more frequently than was previously …

The gene encoding the receptor-tyrosine kinase RET was first discovered more than three
decades ago, and activating RET rearrangements and mutations have since been identified …

Lung cancer in never smokers (LCINS) is a common cause of cancer mortality but its
genomic landscape is poorly characterized. Here high-coverage whole-genome sequencing …

Group 2 innate lymphoid cells (ILC2s) regulate inflammation, tissue repair and metabolic
homeostasis, and are activated by host-derived cytokines and alarmins. Discrete subsets of …

Activating receptor tyrosine kinase RET (rarranged during transfection) gene alterations
have been identified as oncogenic in multiple malignancies. RET gene rearrangements …

Group 3 innate lymphoid cells (ILC3) are major regulators of inflammation and infection at
mucosal barriers. ILC3 development is thought to be programmed, but how ILC3 perceive …

The essential roles played by the immune system in the discrimination between self-versus
non/altered-self and its integral role in promoting host defense against invading microbes …

Signals from sympathetic neurons and immune cells regulate adipocytes and thereby
contribute to fat tissue biology. Interactions between the nervous and immune systems have …

The interplay between the immune and nervous systems has been acknowledged in the
past, but only more recent studies have started to unravel the cellular and molecular players …

Studies in recent years have uncovered the crucial function of neuroimmune interactions in
maintaining tissue homeostasis and protection. Immune and neuronal cells are often …