The extracellular matrix (ECM) is one of the major components of tumors that plays multiple
crucial roles, including mechanical support, modulation of the microenvironment, and a …

Hyaluronan (HA) is a linear polysaccharide with disaccharide repeats of d-glucuronic acid
and N-acetyl-d-glucosamine. It is evolutionarily conserved and abundantly expressed in the …

Premature ovarian insufficiency (POI) is a major cause of female infertility due to early loss of
ovarian function. POI is a heterogeneous condition, and its molecular etiology is unclear. To …

Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Hyaluronan is an extracellular and cell-surface-associated polysaccharide that is
traditionally regarded as a biological'goo'that participates in lubricating joints or holding …

Local translation allows spatial control of gene expression. Here, we performed a dual
protein-mRNA localization screen, using smFISH on 523 human cell lines expressing GFP …

Mitosis is controlled by reversible protein phosphorylation involving specific kinases and
phosphatases. A handful of major mitotic protein kinases, such as the cyclin B–CDK1 …

Despite advances in new approaches for colorectal cancer (CRC) therapy, intravenous
chemotherapy remains one of the main treatment options; however, it has limitations …

The correct formation of new blood vessels from existing vasculature (angiogenesis) is
essential for embryogenesis and the effective repair of damaged or wounded tissues …

Many cancer-associated genes remain to be identified to clarify the underlying molecular
mechanisms of cancer susceptibility and progression. Better understanding is also required …