Long COVID: mechanisms, risk factors and recovery
R Astin, A Banerjee, MR Baker, M Dani… - Experimental …, 2023 - Wiley Online Library
Long COVID, the prolonged illness and fatigue suffered by a small proportion of those
infected with SARS‐CoV‐2, is placing an increasing burden on individuals and society. A …
infected with SARS‐CoV‐2, is placing an increasing burden on individuals and society. A …
Structures and functions of coronavirus replication–transcription complexes and their relevance for SARS-CoV-2 drug design
B Malone, N Urakova, EJ Snijder… - … Reviews Molecular Cell …, 2022 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed millions of
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …
people and continues to cause massive global upheaval. Coronaviruses are positive-strand …
Core mitochondrial genes are down-regulated during SARS-CoV-2 infection of rodent and human hosts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral proteins bind to host
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
mitochondrial proteins, likely inhibiting oxidative phosphorylation (OXPHOS) and stimulating …
The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle
S Ricciardi, AM Guarino, L Giaquinto, EV Polishchuk… - Nature, 2022 - nature.com
Abstract SARS-CoV-2, like other coronaviruses, builds a membrane-bound replication
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …
organelle to enable RNA replication. The SARS-CoV-2 replication organelle is composed of …
A highly photostable and bright green fluorescent protein
M Hirano, R Ando, S Shimozono, M Sugiyama… - Nature …, 2022 - nature.com
The low photostability of fluorescent proteins is a limiting factor in many applications of
fluorescence microscopy. Here we present StayGold, a green fluorescent protein (GFP) …
fluorescence microscopy. Here we present StayGold, a green fluorescent protein (GFP) …
The physiological functions of human peroxisomes
RJA Wanders, M Baes, D Ribeiro… - Physiological …, 2023 - journals.physiology.org
Peroxisomes are subcellular organelles that play a central role in human physiology by
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
catalyzing a range of unique metabolic functions. The importance of peroxisomes for human …
SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB
SARS-CoV-2 is a novel virus that has rapidly spread, causing a global pandemic. In the
majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant …
majority of infected patients, SARS-CoV-2 leads to mild disease; however, in a significant …
SARS-CoV-2 biology and host interactions
The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …
SARS-CoV-2 nsp3 and nsp4 are minimal constituents of a pore spanning replication organelle
L Zimmermann, X Zhao, J Makroczyova… - Nature …, 2023 - nature.com
Coronavirus replication is associated with the remodeling of cellular membranes, resulting
in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified …
in the formation of double-membrane vesicles (DMVs). A DMV-spanning pore was identified …
Volume electron microscopy
Life exists in three dimensions, but until the turn of the century most electron microscopy
methods provided only 2D image data. Recently, electron microscopy techniques capable of …
methods provided only 2D image data. Recently, electron microscopy techniques capable of …